Stadium: Pioneer Field Round: 1
| NCAAF | 2019/11/16 18:00 | Carson–Newman Eagles v Tusculum Pioneers | L | 49-13 |
| NCAAF | 2018/10/27 17:30 | Tusculum Pioneers v Carson–Newman Eagles | W | 41-28 |
| NCAAF | 2021/11/06 17:00 | Mars Hill Lions v Tusculum Pioneers | L | 20-7 |
| NCAAF | 2021/10/30 17:00 | Catawba College v Tusculum Pioneers | L | 31-28 |
| NCAAF | 2021/10/23 18:00 | Tusculum Pioneers v Barton Bulldogs | W | 41-17 |
| NCAAF | 2021/10/16 17:30 | Tusculum Pioneers v Virginia Wise Highland Cavaliers | W | 37-21 |
| NCAAF | 2021/10/09 18:00 | Lenoir Rhyne Bears v Tusculum Pioneers | L | 38-31 |
| NCAAF | 2021/10/02 22:00 | Wingate Bulldogs v Tusculum Pioneers | L | 43-35 |
| NCAAF | 2021/09/25 17:30 | Tusculum Pioneers v Newberry Wolves | L | 19-24 |
| NCAAF | 2021/09/18 17:30 | Tusculum Pioneers v Limestone Saints | W | 24-21 |
| NCAAF | 2021/11/06 17:00 | Carson–Newman Eagles v Limestone Saints | W | 27-21 |
| NCAAF | 2021/10/30 19:00 | Carson–Newman Eagles v Mars Hill Lions | L | 23-49 |
| NCAAF | 2021/10/23 20:00 | Newberry Wolves v Carson–Newman Eagles | L | 34-3 |
| NCAAF | 2021/10/16 17:00 | Carson–Newman Eagles v Lenoir Rhyne Bears | L | 0-59 |
| NCAAF | 2021/10/09 17:00 | Catawba College v Carson–Newman Eagles | L | 33-27 |
| NCAAF | 2021/10/02 18:00 | Barton Bulldogs v Carson–Newman Eagles | L | 31-17 |
| NCAAF | 2021/09/25 16:00 | Virginia Wise Highland Cavaliers v Carson–Newman Eagles | L | 33-7 |
| NCAAF | 2021/09/18 17:00 | Carson–Newman Eagles v Wingate Bulldogs | L | 3-25 |