Stadium: Wilkins Stadium Round: 1
| NCAAF | 2019/10/05 19:00 | Southern Arkansas Muleriders v Southwestern Oklahoma State Bulldogs | W | 42-20 |
| NCAAF | 2018/09/15 23:00 | Southwestern Oklahoma State Bulldogs v Southern Arkansas Muleriders | W | 12-36 |
| NCAAF | 2021/09/02 23:00 | Northwestern Oklahoma State Rangers v Southern Arkansas Muleriders | W | 13-32 |
| NCAAF | 2019/11/16 20:00 | Southern Arkansas Muleriders v Arkansas Monticello Boll Weevils | W | 34-32 |
| NCAAF | 2019/11/09 20:00 | Henderson State Reddies v Southern Arkansas Muleriders | L | 38-31 |
| NCAAF | 2019/11/02 19:00 | Southern Arkansas Muleriders v Ouachita Baptist Tigers | L | 21-38 |
| NCAAF | 2019/10/26 19:00 | East Central Tigers v Southern Arkansas Muleriders | W | 23-24 |
| NCAAF | 2019/10/19 18:30 | Southern Arkansas Muleriders v Southeastern Oklahoma State Savage Storm | W | 49-7 |
| NCAAF | 2019/10/12 18:00 | Northwestern Oklahoma State Rangers v Southern Arkansas Muleriders | W | 7-40 |
| NCAAF | 2019/10/05 19:00 | Southern Arkansas Muleriders v Southwestern Oklahoma State Bulldogs | W | 42-20 |
| NCAAF | 2021/09/02 23:00 | Southwestern Oklahoma State Bulldogs v Henderson State Reddies | L | 13-31 |
| NCAAF | 2019/11/16 21:00 | Northwestern Oklahoma State Rangers v Southwestern Oklahoma State Bulldogs | L | 28-16 |
| NCAAF | 2019/11/09 19:00 | Oklahoma Baptist Bison v Southwestern Oklahoma State Bulldogs | L | 35-21 |
| NCAAF | 2019/11/02 19:00 | Southwestern Oklahoma State Bulldogs v Southern Nazarene | W | 28-7 |
| NCAAF | 2019/10/26 22:30 | Southwestern Oklahoma State Bulldogs v Arkansas Tech Wonder Boys | L | 35-36 |
| NCAAF | 2019/10/19 20:00 | Harding Bisons v Southwestern Oklahoma State Bulldogs | L | 45-14 |
| NCAAF | 2019/10/12 19:00 | Southwestern Oklahoma State Bulldogs v Henderson State Reddies | L | 7-35 |
| NCAAF | 2019/10/05 19:00 | Southern Arkansas Muleriders v Southwestern Oklahoma State Bulldogs | L | 42-20 |