Stadium: Pioneer Field Round: 1
| NCAAF | 2019/09/21 17:00 | Limestone Saints v Tusculum Pioneers | W | 10-38 |
| NCAAF | 2018/09/14 23:00 | Tusculum Pioneers v Limestone Saints | W | 37-10 |
| NCAAF | 2021/09/11 17:00 | Tusculum Pioneers v Chowan Hawks | L | 38-46 |
| NCAAF | 2021/09/04 17:00 | St Augustines Falcons v Tusculum Pioneers | W | 14-58 |
| NCAAF | 2019/11/16 18:00 | Carson–Newman Eagles v Tusculum Pioneers | L | 49-13 |
| NCAAF | 2019/11/09 18:30 | Tusculum Pioneers v Mars Hill Lions | W | 24-7 |
| NCAAF | 2019/11/02 18:30 | Tusculum Pioneers v Catawba College | W | 32-14 |
| NCAAF | 2019/10/26 17:30 | Tusculum Pioneers v Unc Pembroke Braves | W | 23-20 |
| NCAAF | 2019/10/19 17:00 | Virginia Wise Highland Cavaliers v Tusculum Pioneers | W | 19-21 |
| NCAAF | 2019/10/12 18:30 | Tusculum Pioneers v Lenoir Rhyne Bears | L | 14-38 |
| NCAAF | 2021/09/04 23:00 | North Greenville Crusaders v Limestone Saints | L | 37-16 |
| NCAAF | 2019/11/16 18:00 | Newberry Wolves v Limestone Saints | L | 14-7 |
| NCAAF | 2019/11/09 18:00 | Limestone Saints v Carson–Newman Eagles | L | 35-42 |
| NCAAF | 2019/11/02 18:00 | Virginia Wise Highland Cavaliers v Limestone Saints | W | 6-27 |
| NCAAF | 2019/10/26 20:00 | Limestone Saints v Lenoir Rhyne Bears | L | 20-28 |
| NCAAF | 2019/10/19 17:30 | Mars Hill Lions v Limestone Saints | L | 35-28 |
| NCAAF | 2019/10/12 22:00 | Wingate Bulldogs v Limestone Saints | L | 34-3 |
| NCAAF | 2019/10/05 17:00 | Limestone Saints v Catawba College | W | 52-24 |