Stadium: William H. Greene Stadium Round: 1
| NCAAF | 2019/11/16 19:00 | Quincy v William Jewell College Cardinals | L | 47-42 |
| NCAAF | 2018/11/03 22:00 | William Jewell College Cardinals v Quincy | L | 17-23 |
| NCAAF | 2021/11/06 18:00 | Indianapolis Greyhounds v William Jewell College Cardinals | L | 45-14 |
| NCAAF | 2021/10/30 18:00 | William Jewell College Cardinals v Lindenwood | L | 10-53 |
| NCAAF | 2021/10/23 19:00 | Truman Bulldogs v William Jewell College Cardinals | L | 52-0 |
| NCAAF | 2021/10/16 18:00 | Missouri S&t Miners v William Jewell College Cardinals | L | 37-16 |
| NCAAF | 2021/10/09 20:00 | William Jewell College Cardinals v Southwest Baptist University Bearcats | L | 10-55 |
| NCAAF | 2021/10/02 18:00 | McKendree v William Jewell College Cardinals | L | 52-10 |
| NCAAF | 2021/09/25 16:00 | Kentucky Wesleyan v William Jewell College Cardinals | L | 41-21 |
| NCAAF | 2021/09/18 17:00 | William Jewell College Cardinals v Ohio Dominican Panthers | L | 25-35 |
| NCAAF | 2021/11/06 18:00 | Quincy v Southwest Baptist University Bearcats | L | 31-47 |
| NCAAF | 2021/10/30 17:00 | Truman Bulldogs v Quincy | L | 49-28 |
| NCAAF | 2021/10/23 18:00 | Quincy v Indianapolis Greyhounds | L | 21-70 |
| NCAAF | 2021/10/16 20:00 | Quincy v McKendree | L | 48-51 |
| NCAAF | 2021/10/09 18:00 | Lindenwood v Quincy | L | 33-28 |
| NCAAF | 2021/10/02 18:00 | Quincy v Missouri S&t Miners | W | 31-28 |
| NCAAF | 2021/09/25 17:00 | Ashland Eagles v Quincy | L | 63-23 |
| NCAAF | 2021/09/18 18:00 | Quincy v Walsh U. Cavaliers | W | 38-17 |