Stadium: Memorial Stadium Round: 1
| NCAAF | 2019/11/09 17:00 | Clarion Golden Eagles v Mercyhurst | L | 10-57 |
| NCAAF | 2018/11/03 16:00 | Mercyhurst v Clarion Golden Eagles | L | 14-7 |
| NCAAF | 2021/10/23 16:00 | Clarion Golden Eagles v Seton Hill Griffins | L | 0-49 |
| NCAAF | 2021/10/09 18:00 | Clarion Golden Eagles v Iup Crimson Hawks | L | 21-58 |
| NCAAF | 2021/10/02 22:00 | Slippery Rock v Clarion Golden Eagles | L | 75-0 |
| NCAAF | 2021/09/25 17:00 | Gannon University Golden Knights v Clarion Golden Eagles | L | 56-21 |
| NCAAF | 2021/09/18 17:00 | Clarion Golden Eagles v Shippensburg Raiders | L | 33-62 |
| NCAAF | 2021/09/11 17:00 | Clarion Golden Eagles v Millersville University of Pennsylvania Marauders | L | 10-21 |
| NCAAF | 2021/09/04 22:00 | Clarion Golden Eagles v Lake Erie | L | 26-31 |
| NCAAF | 2019/11/16 18:05 | East Stroudsburg Warriors v Clarion Golden Eagles | L | 41-17 |
| NCAAF | 2021/10/23 16:00 | Mercyhurst v Slippery Rock | L | 17-20 |
| NCAAF | 2021/10/16 16:00 | Edinboro v Mercyhurst | W | 20-27 |
| NCAAF | 2021/10/09 16:00 | Mercyhurst v Seton Hill Griffins | L | 17-19 |
| NCAAF | 2021/10/02 19:00 | California Vulcans v Mercyhurst | L | 37-0 |
| NCAAF | 2021/09/25 17:00 | Mercyhurst v Iup Crimson Hawks | L | 13-48 |
| NCAAF | 2021/09/18 17:05 | East Stroudsburg Warriors v Mercyhurst | L | 17-7 |
| NCAAF | 2021/09/11 16:00 | Mercyhurst v West Chester Golden Rams | L | 10-56 |
| NCAAF | 2021/09/04 22:00 | Mercyhurst v Alderson Broaddus Battlers | W | 18-3 |