Stadium: Bobcat Stadium Round: 1
| NCAAF | 2021/11/06 17:00 | Frostburg State v W. Virginia Bobcats | W | 55-14 |
| NCAAF | 2021/10/30 17:00 | Alderson Broaddus Battlers v Frostburg State | W | 7-45 |
| NCAAF | 2021/10/23 17:00 | Fairmont State v Frostburg State | W | 14-49 |
| NCAAF | 2021/10/16 18:00 | Frostburg State v Wheeling Jesuit | W | 41-17 |
| NCAAF | 2021/10/09 16:00 | Notre Dame Falcons v Frostburg State | L | 23-21 |
| NCAAF | 2021/10/02 17:00 | Frostburg State v Unc Pembroke Braves | W | 51-21 |
| NCAAF | 2021/09/25 17:00 | Concord University Mountain Lions v Frostburg State | W | 23-42 |
| NCAAF | 2021/09/18 17:00 | Frostburg State v University of Charleston Golden Eagles | W | 30-24 |
| NCAAF | 2021/11/06 18:00 | West Liberty Hilltoppers v West Virginia State Yellow Jackets | L | 28-33 |
| NCAAF | 2021/10/30 16:00 | West Liberty Hilltoppers v Unc Pembroke Braves | L | 17-27 |
| NCAAF | 2021/10/23 17:00 | Wheeling Jesuit v West Liberty Hilltoppers | L | 26-20 |
| NCAAF | 2021/10/16 17:00 | West Liberty Hilltoppers v Fairmont State | W | 52-31 |
| NCAAF | 2021/10/09 17:00 | Concord University Mountain Lions v West Liberty Hilltoppers | L | 20-16 |
| NCAAF | 2021/10/02 17:00 | West Liberty Hilltoppers v Glenville State Pioneers | W | 20-19 |
| NCAAF | 2021/09/25 17:00 | W. Virginia Bobcats v West Liberty Hilltoppers | W | 0-31 |
| NCAAF | 2021/09/18 18:00 | West Liberty Hilltoppers v Notre Dame Falcons | L | 10-51 |