Stadium: Fred G. Hughes Stadium Round: 1
| NCAAF | 2019/11/16 19:00 | Pittsburgh State Gorillas v Missouri Southern Lions | L | 65-6 |
| NCAAF | 2018/11/10 20:00 | Missouri Southern Lions v Pittsburgh State Gorillas | L | 0-41 |
| NCAAF | 2021/09/25 19:00 | Missouri Southern Lions v Fort Hays State University Tigers | L | 21-42 |
| NCAAF | 2021/09/19 00:00 | Central Oklahoma v Missouri Southern Lions | W | 10-14 |
| NCAAF | 2021/09/11 19:00 | Missouri Southern Lions v Northeastern State Riverhawks | L | 17-21 |
| NCAAF | 2021/09/03 00:00 | Nebraska Kearney v Missouri Southern Lions | L | 38-0 |
| NCAAF | 2019/11/16 19:00 | Pittsburgh State Gorillas v Missouri Southern Lions | L | 65-6 |
| NCAAF | 2019/11/09 21:00 | Missouri Southern Lions v Emporia State | L | 6-29 |
| NCAAF | 2019/11/02 18:00 | Central Oklahoma v Missouri Southern Lions | L | 52-27 |
| NCAAF | 2019/10/26 19:00 | Northeastern State Riverhawks v Missouri Southern Lions | W | 7-86 |
| NCAAF | 2021/09/26 00:00 | Pittsburgh State Gorillas v Emporia State | W | 30-28 |
| NCAAF | 2021/09/18 23:00 | Northeastern State Riverhawks v Pittsburgh State Gorillas | W | 13-48 |
| NCAAF | 2021/09/12 00:00 | Pittsburgh State Gorillas v Nebraska Kearney | L | 17-28 |
| NCAAF | 2021/09/03 00:00 | Central Missouri Mules v Pittsburgh State Gorillas | W | 16-35 |
| NCAAF | 2020/11/14 22:00 | Stephen F. Austin v Pittsburgh State Gorillas | L | 26-7 |
| NCAAF | 2019/11/16 19:00 | Pittsburgh State Gorillas v Missouri Southern Lions | W | 65-6 |
| NCAAF | 2019/11/09 19:00 | Washburn Ichabods Football v Pittsburgh State Gorillas | L | 49-38 |
| NCAAF | 2019/11/02 18:00 | Pittsburgh State Gorillas v Missouri Western Griffons | L | 21-35 |