Stadium: Knoxville Civic Auditorium and Coliseum
| SPHL | 2021/04/30 23:30 | Macon Mayhem v Knoxville Ice Bears | L | 4-1 |
| SPHL | 2021/04/20 23:35 | Knoxville Ice Bears v Macon Mayhem | W | 3-0 |
| SPHL | 2021/04/13 23:35 | Knoxville Ice Bears v Macon Mayhem | L | 1-2 |
| SPHL | 2021/04/02 23:35 | Knoxville Ice Bears v Macon Mayhem | W | 4-2 |
| SPHL | 2021/03/21 20:00 | Macon Mayhem v Knoxville Ice Bears | L | 4-1 |
| SPHL | 2021/03/07 20:00 | Knoxville Ice Bears v Macon Mayhem | W | 4-0 |
| SPHL | 2021/02/21 21:00 | Macon Mayhem v Knoxville Ice Bears | L | 2-1 |
| SPHL | 2021/02/20 23:30 | Macon Mayhem v Knoxville Ice Bears | L | 2-1 |
| SPHL | 2021/05/08 00:35 | Pensacola Ice Flyers v Knoxville Ice Bears | L | 4-2 |
| SPHL | 2021/05/05 23:35 | Knoxville Ice Bears v Pensacola Ice Flyers | L | 2-5 |
| SPHL | 2021/04/30 23:30 | Macon Mayhem v Knoxville Ice Bears | L | 4-1 |
| SPHL | 2021/04/25 21:05 | Knoxville Ice Bears v Pensacola Ice Flyers | L | 1-4 |
| SPHL | 2021/04/25 00:05 | Pensacola Ice Flyers v Knoxville Ice Bears | L | 4-2 |
| SPHL | 2021/04/24 00:30 | Birmingham Bulls v Knoxville Ice Bears | W | 1-5 |
| SPHL | 2021/04/20 23:35 | Knoxville Ice Bears v Macon Mayhem | W | 3-0 |
| SPHL | 2021/04/17 23:35 | Knoxville Ice Bears v Birmingham Bulls | W | 8-5 |
| SPHL | 2021/05/15 22:30 | Macon Mayhem v Pensacola Ice Flyers | L | 1-4 |
| SPHL | 2021/05/15 00:05 | Pensacola Ice Flyers v Macon Mayhem | L | 4-2 |
| SPHL | 2021/05/08 22:30 | Macon Mayhem v Huntsville Havoc | W | 2-1 |
| SPHL | 2021/05/07 00:00 | Huntsville Havoc v Macon Mayhem | W | 1-4 |
| SPHL | 2021/05/02 00:00 | Huntsville Havoc v Macon Mayhem | W | 2-5 |
| SPHL | 2021/04/30 23:30 | Macon Mayhem v Knoxville Ice Bears | W | 4-1 |
| SPHL | 2021/04/28 00:00 | Huntsville Havoc v Macon Mayhem | W | 1-2 |
| SPHL | 2021/04/25 00:00 | Birmingham Bulls v Macon Mayhem | W | 2-4 |