Head to Head
| Malta Premier League | 2020/12/08 13:00 | Sirens v Santa Lucia FC | W | 0-2 |
| Malta Premier League | 2020/02/15 13:00 | Santa Lucia FC v Sirens | L | 0-2 |
| Malta Premier League | 2019/09/28 15:15 | Sirens v Santa Lucia FC | L | 3-1 |
| Europe Friendlies | 2019/07/29 16:01 | Sirens v Santa Lucia FC | D | 1-1 |
| Malta Challenge League | 2019/03/02 13:00 | Santa Lucia FC v Sirens | D | 1-1 |
| Malta Challenge League | 2018/10/06 14:15 | Sirens v Santa Lucia FC | D | 1-1 |
Home History
| Malta Premier League | 2021/09/12 19:00 | Gudja United v Santa Lucia FC | D | 2-2 |
| Malta Premier League | 2021/08/22 17:00 | Santa Lucia FC v Gzira United | D | 1-1 |
| Malta Premier League | 2021/08/14 18:00 | Floriana v Santa Lucia FC | D | 2-2 |
| Europe Friendlies | 2021/07/16 18:00 | Hamrun Spartans v Santa Lucia FC | D | 0-0 |
| Malta Premier League | 2021/03/06 17:00 | Lija Athletic v Santa Lucia FC | L | 3-1 |
| Malta FA Trophy | 2021/03/03 17:30 | Santa Lucia FC v Mosta FC | L | 0-2 |
| Malta Premier League | 2021/02/27 13:00 | Santa Lucia FC v Mosta FC | L | 2-3 |
| Malta Premier League | 2021/02/21 13:00 | Valletta v Santa Lucia FC | L | 1-0 |
Away History
| Malta Premier League | 2021/09/12 15:00 | Sirens v Hibernians | L | 1-3 |
| Malta Premier League | 2021/08/20 17:00 | Sirens v Mosta FC | D | 1-1 |
| Malta Premier League | 2021/08/13 18:00 | Gudja United v Sirens | W | 0-1 |
| Europe Friendlies | 2021/07/24 16:00 | Sirens v Floriana | L | 0-1 |
| Malta Premier League | 2021/03/07 13:00 | Zejtun Corinthians v Sirens | D | 1-1 |
| Malta FA Trophy | 2021/03/04 19:30 | Marsa FC v Sirens | W | 0-1 |
| Malta Premier League | 2021/02/26 20:00 | Sirens v Lija Athletic | D | 1-1 |
| Malta Premier League | 2021/02/21 17:00 | Mosta FC v Sirens | D | 0-0 |