Stadium: Pensacola Bay Center
| SPHL | 2021/05/15 22:30 | Macon Mayhem v Pensacola Ice Flyers | L | 1-4 |
| SPHL | 2021/05/15 00:05 | Pensacola Ice Flyers v Macon Mayhem | L | 4-2 |
| SPHL | 2021/04/16 23:30 | Macon Mayhem v Pensacola Ice Flyers | W | 5-3 |
| SPHL | 2021/04/09 22:05 | Macon Mayhem v Pensacola Ice Flyers | W | 9-3 |
| SPHL | 2021/04/08 23:35 | Macon Mayhem v Pensacola Ice Flyers | W | 5-0 |
| SPHL | 2021/03/28 00:05 | Pensacola Ice Flyers v Macon Mayhem | W | 2-4 |
| SPHL | 2021/03/27 00:35 | Pensacola Ice Flyers v Macon Mayhem | W | 2-3 |
| SPHL | 2021/03/06 00:30 | Macon Mayhem v Pensacola Ice Flyers | L | 3-4 |
| SPHL | 2021/11/20 23:00 | Fayetteville Marksmen v Macon Mayhem | L | 6-2 |
| SPHL | 2021/11/20 00:00 | Fayetteville Marksmen v Macon Mayhem | L | 5-2 |
| SPHL | 2021/11/14 21:00 | Macon Mayhem v Fayetteville Marksmen | L | 1-3 |
| SPHL | 2021/11/13 23:30 | Macon Mayhem v Knoxville Ice Bears | L | 0-9 |
| SPHL | 2021/11/06 00:00 | Huntsville Havoc v Macon Mayhem | L | 6-1 |
| SPHL | 2021/10/30 22:00 | Fayetteville Marksmen v Macon Mayhem | L | 2-1 |
| SPHL | 2021/10/29 23:30 | Macon Mayhem v Fayetteville Marksmen | L | 3-4 |
| SPHL | 2021/10/24 00:15 | Peoria Rivermen v Macon Mayhem | L | 3-2 |
| SPHL | 2021/11/21 01:05 | Pensacola Ice Flyers v Quad City Storm | W | 3-2 |
| SPHL | 2021/11/20 01:05 | Pensacola Ice Flyers v Quad City Storm | L | 3-4 |
| SPHL | 2021/11/14 01:05 | Pensacola Ice Flyers v Huntsville Havoc | L | 2-4 |
| SPHL | 2021/11/13 01:00 | Huntsville Havoc v Pensacola Ice Flyers | L | 5-2 |
| SPHL | 2021/11/07 00:05 | Pensacola Ice Flyers v Birmingham Bulls | W | 4-2 |
| SPHL | 2021/11/06 00:00 | Birmingham Bulls v Pensacola Ice Flyers | W | 1-5 |
| SPHL | 2021/10/31 00:00 | Birmingham Bulls v Pensacola Ice Flyers | W | 1-4 |
| SPHL | 2021/10/30 00:00 | Huntsville Havoc v Pensacola Ice Flyers | L | 4-1 |