[22] John Isner 6-7,6-7,3-6 Brandon Nakashima [84] 2021-08-30 17:35
Stadium: Louis Armstrong Stadium Round: 23 Ground: Hardcourt outdoor
Head to Head
| ATP Atlanta | 2021/08/01 21:00 | Brandon Nakashima v John Isner | 6-7,5-7 |
| ATP Los Cabos | 2021/07/24 03:00 | Brandon Nakashima v John Isner | 7-5,6-4 |
Home History
| ATP Cincinnati | 2021/08/19 16:05 | John Isner v Benoit Paire | 6-7,7-6,1-6 |
| ATP Cincinnati | 2021/08/18 19:35 | Jannik Sinner v John Isner | 7-5,6-7,4-6 |
| ATP Cincinnati | 2021/08/17 17:55 | John Isner v Cameron Norrie | 4-6,7-6,6-4 |
| ATP Toronto | 2021/08/15 00:00 | Daniil Medvedev v John Isner | 6-2,6-2 |
| ATP Toronto | 2021/08/14 01:35 | John Isner v Gael Monfils | 7-6,6-4 |
| ATP Toronto | 2021/08/12 16:35 | Andrey Rublev v John Isner | 5-7,6-7 |
| ATP Toronto | 2021/08/11 15:00 | John Isner v Cristian Garin | 4-6,6-3,6-4 |
| ATP Toronto | 2021/08/10 17:25 | John Isner v Alejandro Davidovich Fokina | 6-4,6-1 |
Away History
| ATP Cincinnati | 2021/08/17 02:00 | Brandon Nakashima v Mackenzie McDonald | 5-7,2-6 |
| ATP Washington | 2021/08/05 18:00 | Denis Kudla v Brandon Nakashima | 3-6,7-6,6-4 |
| ATP Washington | 2021/08/04 18:00 | Brandon Nakashima v Daniel Evans | 7-6,6-0 |
| ATP Washington | 2021/08/03 18:00 | Brandon Nakashima v Alexei Popyrin | 6-3,6-3 |
| ATP Atlanta | 2021/08/01 21:00 | Brandon Nakashima v John Isner | 6-7,5-7 |
| ATP Atlanta | 2021/07/31 19:00 | Brandon Nakashima v Emil Ruusuvuori | 3-6,6-4,6-3 |
| ATP Atlanta | 2021/07/30 16:00 | Brandon Nakashima v Jordan Thompson | 7-6,7-5 |
| ATP Atlanta | 2021/07/28 23:00 | Milos Raonic v Brandon Nakashima | 7-5,3-6,6-7 |