[4] AC Milan 1-2 Atletico Madrid [2] 2021-09-28 19:00
Stadium: Giuseppe Meazza Round: 2
Referee: Cuneyt Cakir Home Manager: Stefano Pioli Away Manager: Diego Simeone
Home History
| Italy Serie A | 2021/09/25 13:00 | Spezia v AC Milan | W | 1-2 |
| Italy Serie A | 2021/09/22 18:45 | AC Milan v Venezia | W | 2-0 |
| Italy Serie A | 2021/09/19 18:45 | Juventus v AC Milan | D | 1-1 |
| UEFA Champions League | 2021/09/15 19:00 | Liverpool v AC Milan | L | 3-2 |
| Italy Serie A | 2021/09/12 16:00 | AC Milan v Lazio | W | 2-0 |
| Italy Serie A | 2021/08/29 18:45 | AC Milan v Cagliari | W | 4-1 |
| Italy Serie A | 2021/08/23 18:45 | Sampdoria v AC Milan | W | 0-1 |
| Elite Club Friendlies | 2021/08/14 18:30 | AC Milan v Panathinaikos | W | 2-1 |
Away History
| Spain La Liga | 2021/09/25 12:00 | CD Alaves v Atletico Madrid | L | 1-0 |
| Spain La Liga | 2021/09/21 17:30 | Getafe v Atletico Madrid | W | 1-2 |
| Spain La Liga | 2021/09/18 14:15 | Atletico Madrid v Athletic Bilbao | D | 0-0 |
| UEFA Champions League | 2021/09/15 19:00 | Atletico Madrid v FC Porto | D | 0-0 |
| Spain La Liga | 2021/09/12 12:00 | Espanyol v Atletico Madrid | W | 1-2 |
| Spain La Liga | 2021/08/29 20:00 | Atletico Madrid v Villarreal | D | 2-2 |
| Spain La Liga | 2021/08/22 17:30 | Atletico Madrid v Elche | W | 1-0 |
| Spain La Liga | 2021/08/15 15:30 | Celta Vigo v Atletico Madrid | W | 1-2 |