| Colombia Regional League | 2021/08/22 19:15 | CFD La Nororiental v Estudiantes de Medellin | L | 1-0 |
| Colombia Regional League | 2021/08/08 19:20 | Estudiantes de Medellin v Inder Girardota | W | 1-0 |
| Colombia Regional League | 2021/07/31 21:08 | Sol de Oriente v Estudiantes de Medellin | W | 0-1 |
| Colombia Regional League | 2021/07/17 19:20 | Estudiantes de Medellin v Envigado FC Reserves | L | 0-3 |
| Colombia Regional League | 2021/07/05 19:12 | Estudiantes de Medellin v Ferrovalvulas FC | D | 0-0 |
| Colombia Regional League | 2021/06/27 17:15 | E.D.P IND. Medellin v Estudiantes de Medellin | W | 0-1 |
| Colombia Regional League | 2021/06/18 17:00 | Estudiantes de Medellin v Club Deportivo La Chalaca | L | 2-3 |
| Colombia Regional League | 2021/03/26 16:19 | Estudiantes de Medellin v E.D.P IND. Medellin | L | 0-1 |
| Colombia Regional League | 2021/08/08 17:15 | Talento y Vida v Independiente Sabaneta | W | 1-2 |
| Colombia Regional League | 2021/07/17 17:13 | Molino Viejo v Independiente Sabaneta | W | 2-3 |
| Colombia Regional League | 2021/07/02 17:19 | Politecnico J.I.C. v Independiente Sabaneta | D | 0-0 |
| Colombia Regional League | 2021/06/26 12:00 | Independiente Sabaneta v FC Leones Reserves | L | 1-2 |
| Colombia Regional League | 2021/06/19 19:17 | CD Gallegol v Independiente Sabaneta | W | 2-3 |