Home History
| United Rugby Championship | 2021/10/02 18:35 | Ospreys v Cardiff Blues | W | 18-14 |
| United Rugby Championship | 2021/09/26 13:00 | Newport Gwent Dragons v Ospreys | W | 23-27 |
| Pro 14 Rainbow Cup | 2021/06/04 17:00 | Connacht v Ospreys | L | 26-19 |
| Pro 14 Rainbow Cup | 2021/05/16 12:00 | Newport Gwent Dragons v Ospreys | W | 26-42 |
| Pro 14 Rainbow Cup | 2021/05/08 18:35 | Scarlets v Ospreys | L | 22-6 |
| Pro 14 Rainbow Cup | 2021/04/24 16:15 | Ospreys v Cardiff Blues | W | 36-14 |
| European Rugby Challenge Cup | 2021/04/03 14:00 | Ospreys v Newcastle Falcons | L | 24-28 |
| Pro 14 Rugby | 2021/03/19 20:15 | Leinster v Ospreys | W | 19-24 |
Away History
| United Rugby Championship | 2021/10/02 14:00 | Glasgow v Sharks | L | 35-24 |
| United Rugby Championship | 2021/09/25 18:35 | Munster v Sharks | L | 42-17 |
| Currie Cup Premier Division | 2021/09/11 15:00 | Blue Bulls v Sharks | L | 44-10 |
| Currie Cup Premier Division | 2021/09/04 15:00 | Sharks v Griquas | W | 28-24 |
| Currie Cup Premier Division | 2021/08/28 17:00 | Sharks v Western Province | L | 24-35 |
| Currie Cup Premier Division | 2021/08/21 12:10 | Golden Lions v Sharks | W | 14-56 |
| Currie Cup Premier Division | 2021/08/15 11:30 | Sharks v Free State Cheetahs | W | 38-31 |
| Currie Cup Premier Division | 2021/08/06 17:00 | Sharks v Blue Bulls | W | 35-28 |