Home History
| United Rugby Championship | 2022/03/19 12:00 | Lions v Munster | W | 23-21 |
| United Rugby Championship | 2022/03/13 14:00 | Lions v Cardiff Blues | W | 37-20 |
| United Rugby Championship | 2022/02/25 19:35 | Leinster v Lions | L | 21-13 |
| United Rugby Championship | 2022/02/12 13:00 | Lions v Stormers | L | 10-32 |
| United Rugby Championship | 2022/02/05 13:00 | Blue Bulls v Lions | L | 21-13 |
| United Rugby Championship | 2022/01/29 13:00 | Lions v Blue Bulls | L | 10-34 |
| United Rugby Championship | 2022/01/22 13:00 | Lions v Sharks | L | 37-47 |
| United Rugby Championship | 2021/12/04 15:00 | Stormers v Lions | W | 19-37 |
Away History
| United Rugby Championship | 2022/03/06 14:00 | Ospreys v Zebre | W | 27-22 |
| United Rugby Championship | 2022/02/19 17:00 | Leinster v Ospreys | L | 29-7 |
| United Rugby Championship | 2022/01/29 17:15 | Ospreys v Edinburgh | W | 23-19 |
| European Rugby Champions Cup | 2022/01/23 13:00 | Sale Sharks v Ospreys | L | 49-10 |
| European Rugby Champions Cup | 2022/01/15 15:15 | Ospreys v Racing Metro | L | 10-25 |
| United Rugby Championship | 2022/01/08 17:15 | Glasgow v Ospreys | L | 38-19 |
| United Rugby Championship | 2022/01/01 17:15 | Scarlets v Ospreys | L | 22-19 |
| European Rugby Champions Cup | 2021/12/18 17:30 | Racing Metro v Ospreys | L | 28-0 |