Saint Francis (PA) 15-35 Eastern Michigan 2021-09-03 23:00
Stadium: Rynearson Stadium Round: 1
Home Manager: Chris Creighton Away Manager: Chris Villarrial
Home History
| NCAAF | 2019/11/23 19:00 | St.Francis (PA) v Delaware State | W | 35-21 |
| NCAAF | 2019/11/16 17:00 | Wagner v St.Francis (PA) | W | 8-42 |
| NCAAF | 2019/11/09 17:00 | St.Francis (PA) v Central Connecticut | L | 31-38 |
| NCAAF | 2019/11/02 16:00 | St.Francis (PA) v Duquesne | L | 21-30 |
| NCAAF | 2019/10/26 16:00 | Sacred Heart v St.Francis (PA) | L | 36-33 |
| NCAAF | 2019/10/19 17:00 | St.Francis (PA) v LIU Brooklyn | W | 30-0 |
| NCAAF | 2019/10/12 16:00 | Robert Morris v St.Francis (PA) | L | 20-17 |
| NCAAF | 2019/09/28 17:00 | St.Francis (PA) v Bryant | W | 16-6 |
Away History
| NCAAF | 2020/12/12 17:00 | Northern Illinois v Eastern Michigan | W | 33-41 |
| NCAAF | 2020/12/05 19:00 | Eastern Michigan v Western Michigan | W | 53-42 |
| NCAAF | 2020/11/27 21:00 | Central Michigan v Eastern Michigan | L | 31-23 |
| NCAAF | 2020/11/19 00:00 | Toledo v Eastern Michigan | L | 45-28 |
| NCAAF | 2020/11/12 00:00 | Eastern Michigan v Ball State | L | 31-38 |
| NCAAF | 2020/11/04 23:00 | Eastern Michigan v Kent State | L | 23-27 |
| NCAAF | 2019/12/27 01:00 | Pittsburgh v Eastern Michigan | L | 34-30 |
| NCAAF | 2019/11/29 17:00 | Kent State v Eastern Michigan | L | 34-26 |