Round: 1
| NCAAF | 2021/11/06 17:00 | Shorter v Erskine Flying Fleet | L | 38-7 |
| NCAAF | 2021/10/30 17:00 | Erskine Flying Fleet v Newberry Wolves | L | 10-48 |
| NCAAF | 2021/10/23 20:00 | Erskine Flying Fleet v Allen Yellow Jackets | W | 47-40 |
| NCAAF | 2021/10/16 20:00 | Erskine Flying Fleet v Bluefield State | W | 24-19 |
| NCAAF | 2021/10/16 17:00 | Erskine Flying Fleet v Bluefield College Rams | W | 24-19 |
| NCAAF | 2021/10/09 22:00 | Savannah State v Erskine Flying Fleet | L | 39-6 |
| NCAAF | 2021/10/02 18:00 | Erskine Flying Fleet v Lynchburg Dragons | W | 59-13 |
| NCAAF | 2021/09/25 17:00 | Erskine Flying Fleet v North Greenville Crusaders | L | 7-38 |
| NCAAF | 2021/11/06 17:00 | Kentucky Thorobreds v Central State | W | 63-0 |
| NCAAF | 2021/10/30 18:00 | Tuskegee v Kentucky Thorobreds | W | 35-42 |
| NCAAF | 2021/10/23 17:00 | Kentucky Thorobreds v Miles Golden Bears | L | 21-28 |
| NCAAF | 2021/10/16 17:00 | Edward Waters Tigers v Kentucky Thorobreds | W | 36-76 |
| NCAAF | 2021/10/09 18:00 | Kentucky Thorobreds v Lane College Dragons | W | 49-14 |
| NCAAF | 2021/10/02 17:00 | Kentucky Thorobreds v Savannah State | L | 17-21 |
| NCAAF | 2021/09/25 19:00 | Kentucky Thorobreds v Benedict College | W | 34-28 |
| NCAAF | 2021/09/18 19:00 | Tennessee State v Kentucky Thorobreds | L | 41-7 |