Stadium: Barron Stadium Round: 1
| NCAAF | 2021/10/30 19:00 | Delta State v Shorter | L | 14-13 |
| NCAAF | 2021/10/23 21:00 | West Florida v Shorter | L | 45-23 |
| NCAAF | 2021/10/16 17:00 | Shorter v Mississippi College Choctaws | L | 7-20 |
| NCAAF | 2021/10/09 17:00 | Shorter v West Alabama Tigers | L | 7-44 |
| NCAAF | 2021/10/02 23:00 | Valdosta State v Shorter | L | 49-13 |
| NCAAF | 2021/09/25 17:00 | Shorter v West Georgia | L | 0-56 |
| NCAAF | 2021/09/18 16:00 | Clark Atlanta University v Shorter | W | 17-38 |
| NCAAF | 2021/09/11 23:00 | Albany State Golden Rams v Shorter | L | 28-12 |
| NCAAF | 2021/10/30 17:00 | Erskine Flying Fleet v Newberry Wolves | L | 10-48 |
| NCAAF | 2021/10/23 20:00 | Erskine Flying Fleet v Allen Yellow Jackets | W | 47-40 |
| NCAAF | 2021/10/16 20:00 | Erskine Flying Fleet v Bluefield State | W | 24-19 |
| NCAAF | 2021/10/16 17:00 | Erskine Flying Fleet v Bluefield College Rams | W | 24-19 |
| NCAAF | 2021/10/09 22:00 | Savannah State v Erskine Flying Fleet | L | 39-6 |
| NCAAF | 2021/10/02 18:00 | Erskine Flying Fleet v Lynchburg Dragons | W | 59-13 |
| NCAAF | 2021/09/25 17:00 | Erskine Flying Fleet v North Greenville Crusaders | L | 7-38 |
| NCAAF | 2021/09/18 17:00 | Chowan Hawks v Erskine Flying Fleet | L | 49-19 |