Stadium: Schmidt Stadium Round: 1
| NCAAF | 2019/10/19 17:00 | Wilkes Colonels v Delaware Valley Aggies | L | 0-42 |
| NCAAF | 2018/09/15 17:00 | Delaware Valley Aggies v Wilkes Colonels | L | 21-10 |
| NCAAF | 2021/10/30 17:00 | Lycoming Warriors v Wilkes Colonels | L | 30-27 |
| NCAAF | 2021/10/23 17:00 | Wilkes Colonels v Lebanon Valley Flying Dutchmen | W | 30-20 |
| NCAAF | 2021/10/16 17:00 | Widener Pride v Wilkes Colonels | L | 30-13 |
| NCAAF | 2021/10/09 16:00 | Albright Lions v Wilkes Colonels | W | 28-31 |
| NCAAF | 2021/10/02 16:00 | Wilkes Colonels v Stevenson Mustangs | W | 21-14 |
| NCAAF | 2021/09/25 17:00 | Wilkes Colonels v Alvernia Golden Wolves | W | 23-0 |
| NCAAF | 2021/09/18 17:00 | Misericordia Cougars v Wilkes Colonels | W | 15-35 |
| NCAAF | 2021/09/04 17:00 | Wilkes Colonels v Keystone Giants | W | 46-7 |
| NCAAF | 2021/10/30 17:00 | Delaware Valley Aggies v Lebanon Valley Flying Dutchmen | W | 31-3 |
| NCAAF | 2021/10/23 17:00 | Misericordia Cougars v Delaware Valley Aggies | W | 0-35 |
| NCAAF | 2021/10/16 16:00 | Fdu Florham Devils v Delaware Valley Aggies | W | 7-61 |
| NCAAF | 2021/10/09 17:00 | Delaware Valley Aggies v Kings Monarchs | W | 48-15 |
| NCAAF | 2021/10/02 17:00 | Lycoming Warriors v Delaware Valley Aggies | W | 7-32 |
| NCAAF | 2021/09/18 17:00 | Delaware Valley Aggies v Stevenson Mustangs | W | 34-17 |
| NCAAF | 2021/09/11 17:00 | Delaware Valley Aggies v Montclair State Red Hawks | W | 26-2 |
| NCAAF | 2021/09/03 23:00 | Kean Cougars v Delaware Valley Aggies | W | 6-57 |