Stadium: Francis Field Round: 1
| NCAAF | 2019/09/21 17:00 | Northwestern Eagles v Greenville Panthers | W | 14-42 |
| NCAAF | 2018/09/15 17:00 | Greenville Panthers v Northwestern Eagles | L | 7-24 |
| NCAAF | 2021/10/02 17:00 | Martin Luther Knights v Greenville Panthers | W | 14-21 |
| NCAAF | 2021/09/25 18:00 | Trinity I. Trojans v Greenville Panthers | L | 26-21 |
| NCAAF | 2021/09/18 19:00 | Adrian Bulldogs v Greenville Panthers | L | 41-28 |
| NCAAF | 2021/09/11 19:30 | Rockford Regents v Greenville Panthers | W | 42-57 |
| NCAAF | 2021/09/04 18:00 | Greenville Panthers v Millikin Big Blue | W | 37-33 |
| NCAAF | 2019/11/16 18:00 | Greenville Panthers v Minnesota Morris Cougars | W | 34-33 |
| NCAAF | 2019/11/09 19:00 | Greenville Panthers v Iowa Wesleyan | W | 21-0 |
| NCAAF | 2019/11/02 18:00 | Macmurray Highlanders v Greenville Panthers | W | 30-41 |
| NCAAF | 2021/10/02 17:00 | Northwestern Eagles v Finlandia Lions | W | 16-13 |
| NCAAF | 2021/09/25 17:00 | Hope Flying Dutchmen v Northwestern Eagles | L | 52-10 |
| NCAAF | 2021/09/18 23:00 | Northwestern Eagles v Uw-River Falls Falcons | L | 13-71 |
| NCAAF | 2021/09/11 23:00 | Northwestern Eagles v Buena Vista Beavers | L | 21-58 |
| NCAAF | 2021/09/04 18:00 | Wheaton Thunder v Northwestern Eagles | L | 56-0 |
| NCAAF | 2019/11/16 18:00 | Iowa Wesleyan v Northwestern Eagles | W | 6-42 |
| NCAAF | 2019/11/09 18:00 | Northwestern Eagles v Westminster Blue Jays | W | 27-17 |
| NCAAF | 2019/10/26 19:00 | Martin Luther Knights v Northwestern Eagles | L | 41-20 |