Stadium: Bob Shelton Stadium Round: 1
| NCAAF | 2019/10/05 23:00 | Hardin Simmons Cowboys v Texas Lutheran Bulldogs | L | 27-38 |
| NCAAF | 2018/10/20 18:00 | Hardin Simmons Cowboys v Texas Lutheran Bulldogs | W | 58-14 |
| NCAAF | 2021/11/06 18:00 | Austin Kangaroos v Hardin Simmons Cowboys | W | 14-56 |
| NCAAF | 2021/10/30 18:00 | Howard Payne Yellow Jackets v Hardin Simmons Cowboys | W | 14-38 |
| NCAAF | 2021/10/23 18:00 | Hardin Simmons Cowboys v Southwestern Pirates | W | 69-7 |
| NCAAF | 2021/10/16 18:00 | East Texas Baptist Tigers v Hardin Simmons Cowboys | W | 0-34 |
| NCAAF | 2021/10/02 18:00 | Hardin Simmons Cowboys v Mcmurry Warhawks | W | 24-21 |
| NCAAF | 2021/09/25 23:00 | Mary Hardin Baylor v Hardin Simmons Cowboys | L | 34-28 |
| NCAAF | 2021/09/18 18:00 | Hardin Simmons Cowboys v Belhaven Blazers | W | 21-16 |
| NCAAF | 2021/09/11 23:00 | Sul Ross State Lobos v Hardin Simmons Cowboys | W | 0-27 |
| NCAAF | 2021/11/06 18:00 | Texas Lutheran Bulldogs v Southwestern Pirates | L | 14-24 |
| NCAAF | 2021/10/30 18:00 | East Texas Baptist Tigers v Texas Lutheran Bulldogs | W | 13-20 |
| NCAAF | 2021/10/23 18:00 | Texas Lutheran Bulldogs v Mcmurry Warhawks | W | 28-21 |
| NCAAF | 2021/10/16 18:00 | Mary Hardin Baylor v Texas Lutheran Bulldogs | L | 49-3 |
| NCAAF | 2021/10/02 23:00 | Texas Lutheran Bulldogs v Belhaven Blazers | L | 35-42 |
| NCAAF | 2021/09/25 23:00 | Sul Ross State Lobos v Texas Lutheran Bulldogs | L | 12-10 |
| NCAAF | 2021/09/18 18:00 | Texas Lutheran Bulldogs v Trinity Tigers | L | 14-51 |
| NCAAF | 2021/09/11 18:00 | Texas Lutheran Bulldogs v Austin Kangaroos | W | 41-7 |