Stadium: Hoernemann Stadium Round: 1
| NCAAF | 2019/11/09 18:30 | Heidelberg Student Princes v John Carroll Blue Streaks | L | 13-17 |
| NCAAF | 2018/11/03 17:30 | John Carroll Blue Streaks v Heidelberg Student Princes | L | 27-0 |
| NCAAF | 2021/10/30 17:30 | Muskingum Muskies v Heidelberg Student Princes | W | 14-49 |
| NCAAF | 2021/10/23 17:30 | Heidelberg Student Princes v Mount Union | L | 14-49 |
| NCAAF | 2021/10/16 23:00 | Heidelberg Student Princes v Otterbein Cardinals | W | 52-19 |
| NCAAF | 2021/10/09 19:00 | Marietta Pioneers v Heidelberg Student Princes | W | 21-44 |
| NCAAF | 2021/09/25 17:30 | Baldwin Wallace Yellow Jackets v Heidelberg Student Princes | L | 20-10 |
| NCAAF | 2021/09/18 17:30 | Heidelberg Student Princes v Capital Crusaders | W | 48-17 |
| NCAAF | 2021/09/04 22:00 | Adrian Bulldogs v Heidelberg Student Princes | W | 20-48 |
| NCAAF | 2019/11/16 18:30 | Ohio Northern Polar Bears v Heidelberg Student Princes | L | 34-28 |
| NCAAF | 2021/10/30 19:00 | John Carroll Blue Streaks v Wilmington Quakers | W | 50-7 |
| NCAAF | 2021/10/23 17:30 | Marietta Pioneers v John Carroll Blue Streaks | W | 10-19 |
| NCAAF | 2021/10/16 18:00 | John Carroll Blue Streaks v Ohio Northern Polar Bears | W | 27-17 |
| NCAAF | 2021/10/09 17:30 | Capital Crusaders v John Carroll Blue Streaks | W | 7-38 |
| NCAAF | 2021/10/02 17:30 | John Carroll Blue Streaks v Muskingum Muskies | W | 29-7 |
| NCAAF | 2021/09/25 17:30 | John Carroll Blue Streaks v Mount Union | L | 14-28 |
| NCAAF | 2021/09/18 18:00 | Otterbein Cardinals v John Carroll Blue Streaks | W | 17-41 |
| NCAAF | 2021/09/04 17:00 | John Carroll Blue Streaks v Washington And Jefferson Presidents | L | 14-21 |