Stadium: Carl W. Burt Memorial Stadium Round: 1
| NCAAF | 2019/09/28 17:30 | Manchester Spartans v Rose Hulman Engineers | L | 35-52 |
| NCAAF | 2018/09/22 23:00 | Rose Hulman Engineers v Manchester Spartans | L | 19-12 |
| NCAAF | 2021/10/16 17:30 | Mount St. Joseph Lions v Manchester Spartans | L | 28-0 |
| NCAAF | 2021/10/09 17:30 | Manchester Spartans v Defiance Yellow Jackets | W | 22-0 |
| NCAAF | 2021/10/02 17:30 | Franklin College Grizzlies v Manchester Spartans | W | 24-27 |
| NCAAF | 2021/09/18 17:00 | Olivet Comets v Manchester Spartans | L | 59-7 |
| NCAAF | 2021/09/11 22:00 | Manchester Spartans v Alma College Scots | L | 23-47 |
| NCAAF | 2021/09/02 23:00 | Manchester Spartans v Trine Thunder | L | 14-52 |
| NCAAF | 2019/11/16 18:30 | Manchester Spartans v Anderson Ravens | W | 70-54 |
| NCAAF | 2019/11/09 18:30 | Defiance Yellow Jackets v Manchester Spartans | W | 0-19 |
| NCAAF | 2021/10/16 17:30 | Rose Hulman Engineers v Anderson Ravens | W | 62-7 |
| NCAAF | 2021/10/09 18:00 | Rose Hulman Engineers v Hanover | W | 31-21 |
| NCAAF | 2021/10/02 17:30 | Defiance Yellow Jackets v Rose Hulman Engineers | W | 14-63 |
| NCAAF | 2021/09/18 18:00 | Hope Flying Dutchmen v Rose Hulman Engineers | L | 27-20 |
| NCAAF | 2021/09/11 23:00 | Trine Thunder v Rose Hulman Engineers | W | 30-31 |
| NCAAF | 2021/09/04 23:00 | Rose Hulman Engineers v Wabash Little Giants | L | 23-33 |
| NCAAF | 2019/11/16 19:00 | St Johns Johnnies v Rose Hulman Engineers | L | 47-14 |
| NCAAF | 2019/11/09 19:00 | Rose Hulman Engineers v Hanover | L | 13-42 |