Stadium: April Zorn Memorial Stadium Round: 1
| NCAAF | 2019/11/09 19:00 | Monmouth Scots v Knox Prairie Fire | W | 31-3 |
| NCAAF | 2018/11/03 18:00 | Knox Prairie Fire v Monmouth Scots | W | 7-40 |
| NCAAF | 2021/11/06 18:00 | Ripon Red Hawks v Monmouth Scots | W | 21-31 |
| NCAAF | 2021/10/30 18:00 | Monmouth Scots v Lake Forest Foresters | L | 10-24 |
| NCAAF | 2021/10/23 19:00 | Monmouth Scots v Cornell Rams | W | 47-14 |
| NCAAF | 2021/10/16 18:00 | Beloit Buccaneers v Monmouth Scots | W | 3-63 |
| NCAAF | 2021/10/09 18:00 | Monmouth Scots v Chicago Maroons | W | 40-37 |
| NCAAF | 2021/10/02 18:00 | Lawrence Vikings v Monmouth Scots | W | 0-42 |
| NCAAF | 2021/09/18 18:00 | Illinois College Blueboys v Monmouth Scots | W | 27-37 |
| NCAAF | 2021/09/11 19:00 | Monmouth Scots v Grinnell Pioneers | W | 42-7 |
| NCAAF | 2021/11/06 18:00 | Knox Prairie Fire v Cornell Rams | L | 34-35 |
| NCAAF | 2021/10/30 18:00 | Knox Prairie Fire v Lawrence Vikings | W | 56-28 |
| NCAAF | 2021/10/23 18:00 | Illinois College Blueboys v Knox Prairie Fire | L | 27-20 |
| NCAAF | 2021/10/16 18:00 | Grinnell Pioneers v Knox Prairie Fire | W | 28-49 |
| NCAAF | 2021/10/09 18:00 | Knox Prairie Fire v Beloit Buccaneers | W | 42-0 |
| NCAAF | 2021/10/02 19:00 | Chicago Maroons v Knox Prairie Fire | L | 45-10 |
| NCAAF | 2021/09/18 19:00 | Knox Prairie Fire v Lake Forest Foresters | L | 10-41 |
| NCAAF | 2021/09/11 18:00 | Knox Prairie Fire v Ripon Red Hawks | L | 14-20 |