Stadium: Ron and Joyce Schipper Stadium Round: 1
| NCAAF | 2019/10/12 18:00 | Central Dutch v Dubuque Spartans | L | 7-28 |
| NCAAF | 2018/09/22 18:00 | Dubuque Spartans v Central Dutch | W | 13-35 |
| NCAAF | 2021/10/30 18:00 | Luther Norse v Central Dutch | W | 13-76 |
| NCAAF | 2021/10/23 18:00 | Central Dutch v Loras Duhawks | W | 53-19 |
| NCAAF | 2021/10/09 18:00 | Coe Kohawks v Central Dutch | W | 21-55 |
| NCAAF | 2021/10/02 18:00 | Central Dutch v Wartburg Knights | W | 49-24 |
| NCAAF | 2021/09/25 18:00 | Simpson Storm v Central Dutch | W | 16-84 |
| NCAAF | 2021/09/18 18:00 | Central Dutch v Nebraska Wesleyan Prairie Wolves | W | 37-7 |
| NCAAF | 2021/09/11 18:00 | Central Dutch v Kalamazoo Hornets | W | 69-13 |
| NCAAF | 2021/09/04 18:00 | St Olaf Oles v Central Dutch | W | 27-46 |
| NCAAF | 2021/10/30 18:00 | Dubuque Spartans v Coe Kohawks | L | 27-34 |
| NCAAF | 2021/10/23 18:00 | Wartburg Knights v Dubuque Spartans | L | 27-7 |
| NCAAF | 2021/10/16 19:00 | Dubuque Spartans v Simpson Storm | W | 41-28 |
| NCAAF | 2021/10/09 18:00 | Nebraska Wesleyan Prairie Wolves v Dubuque Spartans | W | 14-31 |
| NCAAF | 2021/10/02 18:00 | Dubuque Spartans v Buena Vista Beavers | W | 31-16 |
| NCAAF | 2021/09/18 18:00 | Luther Norse v Dubuque Spartans | W | 2-28 |
| NCAAF | 2021/09/11 23:00 | Uw-La Crosse Eagles v Dubuque Spartans | L | 38-7 |
| NCAAF | 2021/09/04 18:00 | Dubuque Spartans v Marietta Pioneers | W | 30-25 |