Stadium: Carl W. Burt Memorial Stadium Round: 1
| NCAAF | 2019/11/09 18:30 | Defiance Yellow Jackets v Manchester Spartans | W | 0-19 |
| NCAAF | 2019/09/19 23:00 | Manchester Spartans v Defiance Yellow Jackets | W | 52-21 |
| NCAAF | 2018/09/15 22:00 | Manchester Spartans v Defiance Yellow Jackets | W | 57-26 |
| NCAAF | 2021/10/02 17:30 | Franklin College Grizzlies v Manchester Spartans | W | 24-27 |
| NCAAF | 2021/09/18 17:00 | Olivet Comets v Manchester Spartans | L | 59-7 |
| NCAAF | 2021/09/11 22:00 | Manchester Spartans v Alma College Scots | L | 23-47 |
| NCAAF | 2021/09/02 23:00 | Manchester Spartans v Trine Thunder | L | 14-52 |
| NCAAF | 2019/11/16 18:30 | Manchester Spartans v Anderson Ravens | W | 70-54 |
| NCAAF | 2019/11/09 18:30 | Defiance Yellow Jackets v Manchester Spartans | W | 0-19 |
| NCAAF | 2019/11/02 17:30 | Manchester Spartans v Bluffton Beavers | L | 14-26 |
| NCAAF | 2019/10/26 17:30 | Hanover v Manchester Spartans | L | 56-7 |
| NCAAF | 2021/10/02 17:30 | Defiance Yellow Jackets v Rose Hulman Engineers | L | 14-63 |
| NCAAF | 2021/09/25 16:00 | Defiance Yellow Jackets v Alfred State Pioneers | L | 28-35 |
| NCAAF | 2021/09/11 17:30 | Defiance Yellow Jackets v Albion Britons | L | 0-51 |
| NCAAF | 2021/09/02 22:00 | Capital Crusaders v Defiance Yellow Jackets | L | 41-7 |
| NCAAF | 2019/11/16 18:30 | Defiance Yellow Jackets v Bluffton Beavers | W | 10-7 |
| NCAAF | 2019/11/09 18:30 | Defiance Yellow Jackets v Manchester Spartans | L | 0-19 |
| NCAAF | 2019/11/02 17:30 | Rose Hulman Engineers v Defiance Yellow Jackets | L | 53-6 |
| NCAAF | 2019/10/26 17:30 | Franklin College Grizzlies v Defiance Yellow Jackets | L | 28-0 |