Stadium: otterbein memorial stadium Round: 1
| NCAAF | 2019/10/26 17:30 | Otterbein Cardinals v Muskingum Muskies | W | 18-10 |
| NCAAF | 2018/10/20 18:00 | Muskingum Muskies v Otterbein Cardinals | L | 21-14 |
| NCAAF | 2021/10/16 23:00 | Heidelberg Student Princes v Otterbein Cardinals | L | 52-19 |
| NCAAF | 2021/10/02 17:30 | Mount Union v Otterbein Cardinals | L | 55-0 |
| NCAAF | 2021/09/25 17:30 | Ohio Northern Polar Bears v Otterbein Cardinals | L | 56-7 |
| NCAAF | 2021/09/18 18:00 | Otterbein Cardinals v John Carroll Blue Streaks | L | 17-41 |
| NCAAF | 2021/09/11 17:30 | Otterbein Cardinals v Baldwin Wallace Yellow Jackets | L | 10-41 |
| NCAAF | 2021/09/04 16:00 | Otterbein Cardinals v Ohio Wesleyan Battling Bishops | L | 28-32 |
| NCAAF | 2019/11/16 18:30 | Otterbein Cardinals v Wilmington Quakers | L | 27-28 |
| NCAAF | 2019/11/09 18:30 | Marietta Pioneers v Otterbein Cardinals | L | 21-10 |
| NCAAF | 2021/10/16 20:00 | Muskingum Muskies v Baldwin Wallace Yellow Jackets | L | 10-49 |
| NCAAF | 2021/10/02 17:30 | John Carroll Blue Streaks v Muskingum Muskies | L | 29-7 |
| NCAAF | 2021/09/25 17:30 | Muskingum Muskies v Wilmington Quakers | W | 62-14 |
| NCAAF | 2021/09/18 23:00 | Marietta Pioneers v Muskingum Muskies | L | 18-0 |
| NCAAF | 2021/09/11 23:00 | Muskingum Muskies v Ohio Northern Polar Bears | W | 33-31 |
| NCAAF | 2021/09/04 20:00 | Muskingum Muskies v Waynesburg Yellow Jackets | W | 49-6 |
| NCAAF | 2019/11/16 18:30 | Capital Crusaders v Muskingum Muskies | W | 14-51 |
| NCAAF | 2019/11/09 18:30 | Mount Union v Muskingum Muskies | L | 51-3 |