Stadium: Mount Union Stadium Round: 1
| NCAAF | 2019/11/09 18:30 | Mount Union v Muskingum Muskies | W | 51-3 |
| NCAAF | 2018/11/03 17:30 | Muskingum Muskies v Mount Union | W | 10-52 |
| NCAAF | 2021/10/30 18:00 | Mount Union v Ohio Northern Polar Bears | W | 42-35 |
| NCAAF | 2021/10/23 17:30 | Heidelberg Student Princes v Mount Union | W | 14-49 |
| NCAAF | 2021/10/16 17:30 | Mount Union v Capital Crusaders | W | 63-0 |
| NCAAF | 2021/10/09 19:00 | Wilmington Quakers v Mount Union | W | 0-63 |
| NCAAF | 2021/10/02 17:30 | Mount Union v Otterbein Cardinals | W | 55-0 |
| NCAAF | 2021/09/25 17:30 | John Carroll Blue Streaks v Mount Union | W | 14-28 |
| NCAAF | 2021/09/18 17:30 | Mount Union v Baldwin Wallace Yellow Jackets | W | 31-7 |
| NCAAF | 2021/09/04 17:00 | Westminster Titans v Mount Union | W | 7-48 |
| NCAAF | 2021/10/30 17:30 | Muskingum Muskies v Heidelberg Student Princes | L | 14-49 |
| NCAAF | 2021/10/23 18:00 | Otterbein Cardinals v Muskingum Muskies | W | 14-31 |
| NCAAF | 2021/10/16 20:00 | Muskingum Muskies v Baldwin Wallace Yellow Jackets | L | 10-49 |
| NCAAF | 2021/10/02 17:30 | John Carroll Blue Streaks v Muskingum Muskies | L | 29-7 |
| NCAAF | 2021/09/25 17:30 | Muskingum Muskies v Wilmington Quakers | W | 62-14 |
| NCAAF | 2021/09/18 23:00 | Marietta Pioneers v Muskingum Muskies | L | 18-0 |
| NCAAF | 2021/09/11 23:00 | Muskingum Muskies v Ohio Northern Polar Bears | W | 33-31 |
| NCAAF | 2021/09/04 20:00 | Muskingum Muskies v Waynesburg Yellow Jackets | W | 49-6 |