[16] Charlton 0-2 Milton Keynes Dons [3] 2022-02-22 19:45
Stadium: The Valley Round: 35
Referee: Sam Purkiss Home Manager: Johnnie Jackson Away Manager: Liam Manning
Head to Head
| England EFL Trophy | 2022/01/04 19:00 | Charlton v Milton Keynes Dons | W | 1-0 |
| England League 1 | 2021/08/17 18:45 | Milton Keynes Dons v Charlton | L | 2-1 |
| England League 1 | 2021/01/26 19:00 | Milton Keynes Dons v Charlton | W | 0-1 |
| England League 1 | 2020/12/02 19:45 | Charlton v Milton Keynes Dons | L | 0-1 |
| England EFL Cup | 2018/08/14 18:45 | Milton Keynes Dons v Charlton | L | 3-0 |
| England League 1 | 2018/02/17 15:00 | Milton Keynes Dons v Charlton | W | 1-2 |
| England League 1 | 2017/11/18 15:00 | Charlton v Milton Keynes Dons | D | 2-2 |
| England League 1 | 2017/04/04 18:45 | Charlton v Milton Keynes Dons | L | 0-2 |
Home History
| England League 1 | 2022/02/19 15:00 | Charlton v Oxford Utd | L | 0-4 |
| England League 1 | 2022/02/12 15:00 | Wigan v Charlton | L | 2-1 |
| England League 1 | 2022/02/08 20:00 | Bolton v Charlton | L | 2-1 |
| England League 1 | 2022/02/05 15:00 | Charlton v AFC Wimbledon | W | 3-2 |
| England League 1 | 2022/01/31 19:45 | Portsmouth v Charlton | W | 1-2 |
| England EFL Trophy | 2022/01/25 19:00 | Hartlepool v Charlton | D | 2-2 |
| England League 1 | 2022/01/22 15:00 | Charlton v Fleetwood Town | W | 2-0 |
| England League 1 | 2022/01/15 15:00 | Cheltenham v Charlton | D | 1-1 |
Away History
| England League 1 | 2022/02/19 15:00 | Sunderland v Milton Keynes Dons | W | 1-2 |
| England League 1 | 2022/02/12 15:00 | Milton Keynes Dons v Ipswich | D | 0-0 |
| England League 1 | 2022/02/08 19:45 | Fleetwood Town v Milton Keynes Dons | D | 1-1 |
| England League 1 | 2022/02/05 15:00 | Milton Keynes Dons v Lincoln City | W | 2-1 |
| England League 1 | 2022/01/29 15:00 | Wycombe v Milton Keynes Dons | W | 0-1 |
| England League 1 | 2022/01/25 19:45 | Burton Albion v Milton Keynes Dons | W | 0-1 |
| England League 1 | 2022/01/22 15:00 | Milton Keynes Dons v Doncaster | L | 0-1 |
| England League 1 | 2022/01/15 15:00 | Portsmouth v Milton Keynes Dons | W | 1-2 |