Stadium: Francis Field Round: 1
| NCAAF | 2019/11/16 18:00 | Greenville Panthers v Minnesota Morris Cougars | W | 34-33 |
| NCAAF | 2019/11/09 19:00 | Greenville Panthers v Iowa Wesleyan | W | 21-0 |
| NCAAF | 2019/11/02 18:00 | Macmurray Highlanders v Greenville Panthers | W | 30-41 |
| NCAAF | 2019/10/26 17:00 | Crown Storm v Greenville Panthers | W | 6-32 |
| NCAAF | 2019/10/19 18:00 | Greenville Panthers v St Scholastica Saints | W | 40-34 |
| NCAAF | 2019/10/05 18:00 | Greenville Panthers v Westminster Blue Jays | W | 36-0 |
| NCAAF | 2019/09/28 17:00 | Martin Luther Knights v Greenville Panthers | L | 43-14 |
| NCAAF | 2019/09/21 17:00 | Northwestern Eagles v Greenville Panthers | W | 14-42 |
| NCAAF | 2019/11/16 19:00 | Millikin Big Blue v North Central Illinois | L | 32-59 |
| NCAAF | 2019/11/09 19:00 | Washington Bears v Millikin Big Blue | W | 28-35 |
| NCAAF | 2019/11/02 18:00 | Illinois Wesleyan Titans v Millikin Big Blue | L | 40-12 |
| NCAAF | 2019/10/26 18:00 | Millikin Big Blue v Elmhurst Bluejays | W | 34-0 |
| NCAAF | 2019/10/19 23:00 | Millikin Big Blue v Carthage Red Men | L | 50-53 |
| NCAAF | 2019/10/12 19:00 | Carroll Pioneers v Millikin Big Blue | W | 7-30 |
| NCAAF | 2019/10/05 18:00 | Augustana Augie v Millikin Big Blue | L | 40-14 |
| NCAAF | 2019/09/28 23:00 | Millikin Big Blue v Wheaton Thunder | L | 0-62 |