Stadium: Schmidt Stadium Round: 1
| NCAAF | 2019/11/16 17:00 | Kings Monarchs v Wilkes Colonels | W | 14-24 |
| NCAAF | 2019/11/09 17:00 | Wilkes Colonels v Stevenson Mustangs | L | 21-42 |
| NCAAF | 2019/11/02 17:00 | Wilkes Colonels v Fdu Florham Devils | W | 45-20 |
| NCAAF | 2019/10/26 17:00 | Misericordia Cougars v Wilkes Colonels | W | 35-36 |
| NCAAF | 2019/10/19 17:00 | Wilkes Colonels v Delaware Valley Aggies | L | 0-42 |
| NCAAF | 2019/10/12 17:00 | Albright Lions v Wilkes Colonels | W | 40-42 |
| NCAAF | 2019/10/05 17:00 | Wilkes Colonels v Alvernia Golden Wolves | W | 45-12 |
| NCAAF | 2019/09/21 17:00 | Lycoming Warriors v Wilkes Colonels | W | 17-24 |