[4] Giannina 1-0 Panathinaikos [2] 2021-09-18 17:30
Stadium: Zosimades National Stadium Round: 2
Referee: Ioannis Papadopoulos Home Manager: Iraklis Metaxas Away Manager: Ivan Jovanovic
Head to Head
| Greece Super League 1 | 2021/03/06 17:30 | Giannina v Panathinaikos | W | 1-0 |
| Greece Cup | 2021/03/03 18:00 | Panathinaikos v Giannina | W | 1-2 |
| Greece Cup | 2021/02/18 13:00 | Giannina v Panathinaikos | W | 2-1 |
| Greece Super League 1 | 2020/12/12 17:30 | Panathinaikos v Giannina | L | 2-0 |
| Greece Cup | 2020/01/15 15:15 | Panathinaikos v Giannina | L | 3-1 |
| Greece Cup | 2020/01/08 15:15 | Giannina v Panathinaikos | W | 1-0 |
| Greece Super League 1 | 2019/02/09 17:30 | Giannina v Panathinaikos | W | 1-0 |
| Greece Super League 1 | 2018/09/29 16:00 | Panathinaikos v Giannina | L | 2-1 |
Home History
| Greece Super League 1 | 2021/09/12 16:00 | PAOK Salonika v Giannina | W | 0-1 |
| Europe Friendlies | 2021/09/01 15:00 | Giannina v Thesprotos | W | 4-1 |
| Europe Friendlies | 2021/08/28 15:30 | Giannina v Panetolikos | L | 2-3 |
| Europe Friendlies | 2021/08/21 17:30 | Aris Salonika v Giannina | L | 4-1 |
| Europe Friendlies | 2021/08/14 16:00 | Asteras Tripolis v Giannina | L | 1-0 |
| Europe Friendlies | 2021/08/08 16:30 | Panetolikos v Giannina | D | 0-0 |
| Europe Friendlies | 2021/08/04 17:00 | Lamia v Giannina | L | 2-0 |
| Greece Super League 1 | 2021/05/19 14:15 | Giannina v Apollon Smyrnis | L | 0-2 |
Away History
| Greece Super League 1 | 2021/09/11 17:30 | Panathinaikos v Apollon Smyrnis | W | 4-0 |
| World Club Friendlies | 2021/09/04 16:30 | Panathinaikos v Lamia | W | 3-2 |
| Europe Friendlies | 2021/08/28 17:00 | Panathinaikos v Asteras Tripolis | D | 1-1 |
| World Club Friendlies | 2021/08/21 14:30 | Panathinaikos v Panetolikos | L | 1-2 |
| Elite Club Friendlies | 2021/08/14 18:30 | AC Milan v Panathinaikos | L | 2-1 |
| Europe Friendlies | 2021/08/10 18:00 | Panathinaikos v Apoel Nicosia | D | 1-1 |
| Europe Friendlies | 2021/08/06 18:00 | Panathinaikos v NK Lokomotiva Zagreb | D | 2-2 |
| Europe Friendlies | 2021/07/31 14:00 | VVV v Panathinaikos | W | 5-7 |