[11] London Irish 31-31 Sale Sharks [8] 2021-09-26 14:00
Stadium: Brentford Community Stadium Round: 2
Referee: Wayne Barnes
Head to Head
| Premiership Rugby | 2021/03/21 15:00 | Sale Sharks v London Irish | L | 41-13 |
| Premiership Rugby | 2020/12/06 14:30 | London Irish v Sale Sharks | L | 13-21 |
| Premiership Rugby | 2020/03/06 20:00 | Sale Sharks v London Irish | L | 39-0 |
| Premiership Rugby | 2019/10/26 14:00 | London Irish v Sale Sharks | L | 7-41 |
| Premiership Rugby Cup | 2019/10/12 14:00 | London Irish v Sale Sharks | L | 22-27 |
| Premiership Rugby | 2018/02/10 15:00 | London Irish v Sale Sharks | L | 9-13 |
| Premiership Rugby | 2017/09/15 19:00 | Sale Sharks v London Irish | L | 36-7 |
| Premiership Rugby | 2016/04/02 14:00 | London Irish v Sale Sharks | L | 15-30 |
Home History
| Premiership Rugby | 2021/09/18 14:00 | Worcester Warriors v London Irish | L | 36-24 |
| Premiership Rugby | 2021/06/05 15:30 | London Irish v Wasps | L | 36-39 |
| Premiership Rugby | 2021/05/28 18:45 | Gloucester v London Irish | L | 30-28 |
| Premiership Rugby | 2021/05/18 18:45 | London Irish v Exeter Chiefs | L | 12-31 |
| Premiership Rugby | 2021/05/08 14:00 | Newcastle Falcons v London Irish | L | 52-27 |
| Premiership Rugby | 2021/04/24 11:30 | London Irish v Harlequins | L | 21-25 |
| Premiership Rugby | 2021/04/16 18:45 | Northampton v London Irish | L | 44-26 |
| European Rugby Challenge Cup | 2021/04/09 19:00 | Bath v London Irish | L | 26-13 |
Away History
| Premiership Rugby | 2021/09/18 16:00 | Sale Sharks v Bath | W | 20-19 |
| Premiership Rugby | 2021/06/19 15:30 | Exeter Chiefs v Sale Sharks | L | 40-30 |
| Premiership Rugby | 2021/06/12 14:00 | Exeter Chiefs v Sale Sharks | L | 20-19 |
| Premiership Rugby | 2021/06/04 18:45 | Sale Sharks v Harlequins | W | 45-12 |
| Premiership Rugby | 2021/05/28 18:45 | Sale Sharks v Bristol | W | 22-12 |
| Premiership Rugby | 2021/05/14 18:45 | Bath v Sale Sharks | W | 20-24 |
| Premiership Rugby | 2021/05/07 18:45 | Sale Sharks v Leicester | W | 26-10 |
| Premiership Rugby | 2021/04/24 14:00 | Worcester Warriors v Sale Sharks | W | 32-35 |