[9] Wasps 38-30 London Irish [7] 2021-12-26 15:00
Stadium: Ricoh Arena Round: 11
Referee: Craig Maxwell-Keys
Head to Head
| Premiership Rugby | 2021/06/05 15:30 | London Irish v Wasps | W | 36-39 |
| Premiership Rugby | 2021/02/27 15:00 | Wasps v London Irish | L | 10-16 |
| Premiership Rugby | 2020/03/01 14:30 | London Irish v Wasps | W | 26-36 |
| Premiership Rugby | 2019/10/20 14:00 | Wasps v London Irish | L | 26-29 |
| Premiership Rugby | 2018/03/04 15:00 | Wasps v London Irish | W | 24-16 |
| LV Cup | 2018/01/27 15:00 | London Irish v Wasps | L | 66-7 |
| Premiership Rugby | 2017/11/26 15:00 | London Irish v Wasps | W | 13-17 |
| Premiership Rugby | 2016/05/07 14:30 | Wasps v London Irish | W | 38-12 |
Home History
| European Rugby Champions Cup | 2021/12/19 15:15 | Toulouse v Wasps | D | 0-0 |
| European Rugby Champions Cup | 2021/12/12 15:15 | Wasps v Munster | L | 14-35 |
| Premiership Rugby | 2021/12/04 15:00 | Worcester Warriors v Wasps | L | 32-31 |
| Premiership Rugby | 2021/11/26 19:45 | Wasps v Gloucester | L | 33-35 |
| Premiership Rugby Cup | 2021/11/20 13:30 | Wasps v Leicester | L | 7-55 |
| Premiership Rugby Cup | 2021/11/13 15:00 | Newcastle Falcons v Wasps | L | 34-27 |
| Premiership Rugby | 2021/11/07 16:30 | Wasps v Harlequins | L | 16-26 |
| Premiership Rugby | 2021/10/30 14:00 | Bath v Wasps | W | 17-27 |
Away History
| European Rugby Challenge Cup | 2021/12/19 15:15 | London Irish v Brive | D | 0-0 |
| European Rugby Challenge Cup | 2021/12/11 20:00 | Pau v London Irish | W | 17-33 |
| Premiership Rugby | 2021/12/04 15:00 | London Irish v Newcastle Falcons | W | 43-21 |
| Premiership Rugby | 2021/11/27 15:00 | Harlequins v London Irish | W | 19-22 |
| Premiership Rugby Cup | 2021/11/19 19:45 | London Irish v Saracens | W | 29-20 |
| Premiership Rugby Cup | 2021/11/13 15:30 | Northampton v London Irish | W | 26-36 |
| Premiership Rugby | 2021/11/06 15:00 | Saracens v London Irish | D | 34-34 |
| Premiership Rugby | 2021/10/30 14:00 | London Irish v Bristol | L | 33-45 |