London Irish 22-42 Northampton 2022-03-26 15:00
Stadium: Brentford Community Stadium Round: 21
Referee: Wayne Barnes
Head to Head
| Premiership Rugby Cup | 2021/11/13 15:30 | Northampton v London Irish | W | 26-36 |
| Premiership Rugby | 2021/10/02 13:00 | Northampton v London Irish | L | 23-21 |
| Premiership Rugby | 2021/04/16 18:45 | Northampton v London Irish | L | 44-26 |
| Premiership Rugby | 2020/08/22 13:00 | London Irish v Northampton | L | 3-27 |
| Premiership Rugby | 2020/01/24 19:45 | Northampton v London Irish | W | 16-20 |
| Premiership Rugby | 2018/02/17 15:00 | Northampton v London Irish | L | 25-17 |
| Premiership Rugby | 2017/09/24 14:00 | London Irish v Northampton | L | 25-40 |
| Premiership Rugby | 2016/02/13 15:00 | Northampton v London Irish | L | 35-7 |
Home History
| Premiership Rugby Cup | 2022/03/18 19:45 | London Irish v Harlequins | W | 34-19 |
| Premiership Rugby | 2022/03/12 15:00 | Leicester v London Irish | L | 47-28 |
| Premiership Rugby | 2022/03/05 15:00 | London Irish v Worcester Warriors | W | 43-12 |
| Premiership Rugby | 2022/02/25 19:45 | Sale Sharks v London Irish | D | 27-27 |
| Premiership Rugby | 2022/02/19 15:00 | London Irish v Saracens | W | 32-30 |
| Premiership Rugby | 2022/02/11 19:45 | Bristol v London Irish | W | 32-49 |
| Premiership Rugby | 2022/02/04 19:45 | Gloucester v London Irish | L | 24-7 |
| Premiership Rugby | 2022/01/29 15:00 | London Irish v Exeter Chiefs | W | 18-14 |
Away History
| Premiership Rugby Cup | 2022/03/19 15:00 | Saracens v Northampton | W | 35-46 |
| Premiership Rugby | 2022/03/13 15:00 | Northampton v Wasps | W | 27-22 |
| Premiership Rugby | 2022/03/05 15:00 | Gloucester v Northampton | L | 35-30 |
| Premiership Rugby | 2022/02/27 13:00 | Northampton v Exeter Chiefs | L | 31-34 |
| Premiership Rugby | 2022/02/19 15:00 | Northampton v Sale Sharks | L | 21-22 |
| Premiership Rugby | 2022/02/11 19:45 | Leicester v Northampton | L | 35-20 |
| Premiership Rugby | 2022/01/29 15:00 | Worcester Warriors v Northampton | W | 13-29 |
| European Rugby Champions Cup | 2022/01/23 15:15 | Racing Metro v Northampton | L | 28-0 |