[3] Harlequins 28-24 Gloucester [5] 2022-05-21 14:00
Stadium: London Round: 25
Referee: Craig Maxwell-Keys
Head to Head
| Premiership Rugby | 2022/01/02 15:00 | Gloucester v Harlequins | W | 17-20 |
| Premiership Rugby | 2021/03/20 14:00 | Harlequins v Gloucester | W | 59-24 |
| Premiership Rugby | 2020/12/06 16:15 | Gloucester v Harlequins | W | 24-34 |
| Premiership Rugby | 2020/09/14 18:45 | Gloucester v Harlequins | W | 15-28 |
| Premiership Rugby | 2019/12/01 15:00 | Harlequins v Gloucester | W | 23-19 |
| Premiership Rugby Cup | 2019/10/05 14:00 | Harlequins v Gloucester | W | 40-31 |
| Premiership Rugby | 2019/03/10 13:00 | Harlequins v Gloucester | L | 7-29 |
| Premiership Rugby | 2018/09/29 14:00 | Gloucester v Harlequins | W | 25-27 |
Home History
| Premiership Rugby | 2022/04/29 18:45 | Northampton v Harlequins | L | 32-31 |
| Premiership Rugby | 2022/04/23 14:00 | Harlequins v Leicester | W | 26-20 |
| European Rugby Champions Cup | 2022/04/16 11:30 | Harlequins v Montpellier | W | 33-20 |
| European Rugby Champions Cup | 2022/04/10 12:00 | Montpellier v Harlequins | L | 40-26 |
| Premiership Rugby | 2022/04/03 14:00 | London Irish v Harlequins | W | 14-41 |
| Premiership Rugby Cup | 2022/03/29 18:45 | Harlequins v Sale Sharks | L | 29-34 |
| Premiership Rugby Cup | 2022/03/18 19:45 | London Irish v Harlequins | L | 34-19 |
| Premiership Rugby | 2022/03/13 15:00 | Bristol v Harlequins | W | 29-38 |
Away History
| European Rugby Challenge Cup | 2022/05/06 19:00 | Gloucester v Saracens | L | 15-44 |
| Premiership Rugby | 2022/04/30 14:00 | Gloucester v Bath | W | 64-0 |
| Premiership Rugby Cup | 2022/04/27 18:45 | Gloucester v Worcester Warriors | L | 25-39 |
| Premiership Rugby | 2022/04/22 18:45 | Bristol v Gloucester | L | 29-28 |
| European Rugby Challenge Cup | 2022/04/16 19:00 | Gloucester v Northampton | W | 31-21 |
| European Rugby Challenge Cup | 2022/04/09 19:00 | Newport Gwent Dragons v Gloucester | W | 21-26 |
| Premiership Rugby | 2022/04/02 14:00 | Gloucester v Wasps | L | 21-27 |
| Premiership Rugby Cup | 2022/03/30 18:45 | Bristol v Gloucester | W | 15-43 |