Stadium: Melvin Jones Gym Round: 3
| Italy Serie B | 2021/10/10 16:00 | Virtus Salerno v Action Now Monopoli | L | 78-72 |
| Italy Serie B | 2021/10/03 16:00 | Action Now Monopoli v Geko PSA Sant'Antimo | W | 79-74 |
| Italy Serie B Super Cup | 2021/09/15 18:30 | Lions Bisceglie v Action Now Monopoli | L | 81-68 |
| Italy Serie B Super Cup | 2021/09/12 16:30 | CJ Basket Taranto v Action Now Monopoli | W | 68-76 |
| Club Friendlies | 2021/09/08 16:30 | Frata Nardò v Action Now Monopoli | L | 81-59 |
| Italy Serie B | 2021/05/26 17:00 | Bava Virtus Pozzuoli v Action Now Monopoli | W | 68-69 |
| Italy Serie B | 2021/05/23 17:00 | Action Now Monopoli v Bava Virtus Pozzuoli | W | 83-60 |
| Italy Serie B | 2021/05/21 17:30 | Action Now Monopoli v Bava Virtus Pozzuoli | W | 73-64 |
| Italy Serie B | 2021/10/10 17:30 | Virtus Kleb Ragusa v Lions Bisceglie | L | 63-69 |
| Italy Serie B | 2021/10/02 16:00 | CJ Basket Taranto v Virtus Kleb Ragusa | W | 74-75 |
| Italy Serie B Super Cup | 2021/09/15 19:00 | Agrigento v Virtus Kleb Ragusa | L | 88-71 |
| Italy Serie B | 2021/05/08 15:00 | Virtus Kleb Ragusa v Coelsanus Robur Et Fides Varese | W | 92-75 |
| Italy Serie B | 2021/05/02 18:30 | Virtus Kleb Ragusa v Juvi Cremona | L | 73-81 |
| Italy Serie B | 2021/04/25 14:00 | Fiorenzuola Bees v Virtus Kleb Ragusa | L | 68-58 |
| Italy Serie B | 2021/04/18 13:00 | Corona Platina Piadena MG.Kvis v Virtus Kleb Ragusa | W | 64-67 |
| Italy Serie B | 2021/04/11 17:00 | Virtus Kleb Ragusa v Pavia | L | 65-67 |