Stadium: PalaLuiss Round: 10
| Italy National Serie B | 2021/11/28 17:00 | Real Sebastiani Rieti v Luiss Roma | L | 72-60 |
| Italy National Serie B | 2021/11/20 17:00 | Luiss Roma v Luciana Mosconi Ancona | L | 64-68 |
| Italy National Serie B | 2021/11/14 17:00 | Rennova Teramo v Luiss Roma | L | 74-67 |
| Italy National Serie B | 2021/11/06 17:00 | Luiss Roma v Raggisolaris Faenza | L | 51-63 |
| Italy National Serie B | 2021/10/31 17:00 | Imola v Luiss Roma | L | 78-60 |
| Italy National Serie B | 2021/10/23 16:00 | Luiss Roma v Sutor Montegranaro | L | 62-70 |
| Italy National Serie B | 2021/10/16 16:00 | Luiss Roma v Roseto | W | 93-80 |
| Italy National Serie B | 2021/10/09 17:00 | Logimatic Group Ozzano v Luiss Roma | L | 95-70 |
| Italy National Serie B | 2021/11/28 17:00 | Virtus Civitanova Marche v Roseto | L | 53-77 |
| Italy National Serie B | 2021/11/21 17:00 | NPC Rieti v Virtus Civitanova Marche | L | 58-33 |
| Italy National Serie B | 2021/11/14 17:00 | Virtus Civitanova Marche v Goldengas Senigallia | L | 54-59 |
| Italy National Serie B | 2021/11/07 17:00 | Jesi Academy v Virtus Civitanova Marche | L | 74-70 |
| Italy National Serie B | 2021/10/31 17:00 | Virtus Civitanova Marche v Logimatic Group Ozzano | L | 68-74 |
| Italy National Serie B | 2021/10/24 16:00 | Virtus Civitanova Marche v Rinascita Basket Rimini | L | 40-69 |
| Italy National Serie B | 2021/10/17 16:00 | Real Sebastiani Rieti v Virtus Civitanova Marche | L | 85-35 |
| Italy National Serie B | 2021/10/10 16:00 | Virtus Civitanova Marche v Sutor Montegranaro | W | 67-52 |