Stadium: Melvin Jones Gym Round: 1
| Italy National Serie B | 2021/03/28 16:00 | PSA Sant'Antimo v Action Now Monopoli | L | 87-81 |
| Italy Serie B Super Cup | 2021/09/15 18:30 | Lions Bisceglie v Action Now Monopoli | L | 81-68 |
| Italy Serie B Super Cup | 2021/09/12 16:30 | CJ Basket Taranto v Action Now Monopoli | W | 68-76 |
| Club Friendlies | 2021/09/08 16:30 | Frata Nardò v Action Now Monopoli | L | 81-59 |
| Italy National Serie B | 2021/05/26 17:00 | Bava Virtus Pozzuoli v Action Now Monopoli | W | 68-69 |
| Italy National Serie B | 2021/05/23 17:00 | Action Now Monopoli v Bava Virtus Pozzuoli | W | 83-60 |
| Italy National Serie B | 2021/05/21 17:30 | Action Now Monopoli v Bava Virtus Pozzuoli | W | 73-64 |
| Italy National Serie B | 2021/05/18 17:00 | Bava Virtus Pozzuoli v Action Now Monopoli | L | 70-52 |
| Italy National Serie B | 2021/05/16 16:00 | Bava Virtus Pozzuoli v Action Now Monopoli | L | 80-60 |
| Italy Serie B Super Cup | 2021/09/15 18:30 | Virtus Salerno v PSA Sant'Antimo | L | 78-75 |
| Italy National Serie B | 2021/05/23 16:00 | PSA Sant'Antimo v Ristopro Fabriano | L | 67-76 |
| Italy National Serie B | 2021/05/21 18:30 | PSA Sant'Antimo v Ristopro Fabriano | L | 78-86 |
| Italy National Serie B | 2021/05/18 18:30 | Ristopro Fabriano v PSA Sant'Antimo | L | 99-70 |
| Italy National Serie B | 2021/05/16 17:00 | Ristopro Fabriano v PSA Sant'Antimo | W | 72-80 |
| Italy National Serie B | 2021/05/06 18:30 | PSA Sant'Antimo v Ruvo di Puglia | L | 81-85 |
| Italy National Serie B | 2021/05/02 16:00 | Mastria Sport Academy Catanzaro v PSA Sant'Antimo | W | 75-80 |
| Italy National Serie B | 2021/04/25 16:00 | PSA Sant'Antimo v CJ Basket Taranto | W | 84-83 |