[9] IA Sud America 0-2 Nacional De Football [14] 2021-09-25 21:30
Stadium: Jardines Del Hipódromo Round: 3
Referee: Agustin Berisso Home Manager: Claudio Biaggio Away Manager: Martin Ricardo Liguera Lopez
Head to Head
| Uruguay Apertura | 2021/05/30 23:30 | Nacional De Football v IA Sud America | L | 1-0 |
| Uruguay Clausura | 2017/12/03 20:00 | IA Sud America v Nacional De Football | W | 3-2 |
| Uruguay Torneo Intermedio | 2017/07/01 21:00 | IA Sud America v Nacional De Football | L | 0-3 |
| Uruguay Apertura | 2017/05/13 18:30 | Nacional De Football v IA Sud America | L | 4-3 |
| Uruguay Apertura | 2016/10/16 22:15 | Nacional De Football v IA Sud America | L | 1-0 |
| Uruguay Clausura | 2016/04/30 22:00 | IA Sud America v Nacional De Football | D | 1-1 |
| Uruguay Apertura | 2015/10/24 21:00 | Nacional De Football v IA Sud America | W | 1-2 |
| Uruguay Clausura | 2015/02/21 19:30 | Nacional De Football v IA Sud America | W | 1-2 |
Home History
| Uruguay Clausura | 2021/09/18 18:30 | Villa Espanola v IA Sud America | W | 1-2 |
| Uruguay Clausura | 2021/09/11 16:15 | IA Sud America v Torque | L | 1-2 |
| Uruguay Apertura | 2021/08/22 18:00 | IA Sud America v Penarol | D | 1-1 |
| Uruguay Apertura | 2021/08/14 14:00 | Rentistas v IA Sud America | W | 1-2 |
| Uruguay Apertura | 2021/08/09 15:45 | IA Sud America v Montevideo Wanderers | W | 1-0 |
| Uruguay Apertura | 2021/07/31 18:00 | Boston River v IA Sud America | L | 2-0 |
| Uruguay Apertura | 2021/07/24 18:00 | IA Sud America v Atletico Fenix Montevideo | D | 1-1 |
| Uruguay Apertura | 2021/07/10 18:00 | Plaza Colonia v IA Sud America | L | 1-0 |
Away History
| Uruguay Clausura | 2021/09/19 18:30 | Nacional De Football v Club Atletico Progreso | L | 0-1 |
| Uruguay Clausura | 2021/09/11 21:30 | Cerro Largo v Nacional De Football | D | 1-1 |
| Uruguay Apertura | 2021/08/21 18:00 | CA River Plate v Nacional De Football | L | 2-0 |
| Uruguay Apertura | 2021/08/15 21:00 | Nacional De Football v Liverpool Montevideo | W | 1-0 |
| Uruguay Apertura | 2021/08/08 21:00 | Cerrito v Nacional De Football | L | 2-0 |
| Uruguay Apertura | 2021/08/01 23:30 | Nacional De Football v Deportivo Maldonado | W | 2-0 |
| Uruguay Apertura | 2021/07/25 21:00 | Nacional De Football v Villa Espanola | W | 3-0 |
| Copa Sudamericana | 2021/07/23 00:30 | Penarol v Nacional De Football | W | 0-1 |