Head to Head
| Bolivia Apertura | 2021/05/01 23:30 | Guabira v Real Santa Cruz | L | 1-0 |
| Bolivia Apertura | 2020/12/29 19:00 | Real Santa Cruz v Guabira | D | 4-4 |
| Bolivia Apertura | 2020/03/15 21:15 | Guabira v Real Santa Cruz | L | 1-0 |
Home History
| Bolivia Apertura | 2021/09/21 23:00 | Real Potosi v Real Santa Cruz | L | 3-0 |
| Bolivia Apertura | 2021/09/18 19:00 | Real Santa Cruz v Royal Pari FC | W | 2-1 |
| Bolivia Apertura | 2021/09/14 19:00 | Always Ready v Real Santa Cruz | L | 4-0 |
| Bolivia Apertura | 2021/08/23 19:00 | Real Santa Cruz v Atletico Palmaflor Vinto | W | 1-0 |
| Bolivia Apertura | 2021/08/20 00:15 | Jorge Wilstermann v Real Santa Cruz | L | 5-1 |
| Bolivia Apertura | 2021/08/14 23:30 | The Strongest v Real Santa Cruz | W | 1-2 |
| Bolivia Apertura | 2021/08/07 19:00 | Real Santa Cruz v Oriente Petrolero | D | 0-0 |
| Bolivia Apertura | 2021/08/03 22:15 | Nacional Potosi v Real Santa Cruz | D | 2-2 |
Away History
| Bolivia Apertura | 2021/09/21 19:00 | Guabira v San Jose | W | 4-0 |
| Bolivia Apertura | 2021/09/17 23:30 | Real Tomayapo v Guabira | D | 1-1 |
| Bolivia Apertura | 2021/09/13 18:55 | Guabira v Club Aurora | W | 4-0 |
| Bolivia Apertura | 2021/08/22 21:15 | Bolivar v Guabira | L | 6-0 |
| Bolivia Apertura | 2021/08/17 23:30 | Guabira v Blooming | W | 4-2 |
| Bolivia Apertura | 2021/08/13 21:15 | Independiente Petrolero v Guabira | L | 2-1 |
| Bolivia Apertura | 2021/08/09 19:00 | Guabira v Real Potosi | W | 3-0 |
| Bolivia Apertura | 2021/08/05 19:00 | Royal Pari FC v Guabira | D | 1-1 |