[8] ARZ Coyotes 1-2 BUF Sabres [1] 2021-10-16 17:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Andre Tourigny
Head to Head
| NHL | 2020/03/01 01:00 | BUF Sabres v ARZ Coyotes | W | 2-5 |
| NHL | 2019/10/28 23:00 | ARZ Coyotes v BUF Sabres | W | 3-2 |
| NHL | 2018/12/14 00:00 | ARZ Coyotes v BUF Sabres | L | 1-3 |
| NHL | 2018/10/14 01:00 | BUF Sabres v ARZ Coyotes | L | 3-0 |
| NHL | 2018/03/21 23:00 | ARZ Coyotes v BUF Sabres | W | 4-1 |
| NHL | 2017/11/03 02:00 | BUF Sabres v ARZ Coyotes | L | 5-4 |
| NHL | 2017/03/03 00:00 | ARZ Coyotes v BUF Sabres | L | 3-6 |
| NHL | 2017/02/27 01:30 | BUF Sabres v ARZ Coyotes | W | 2-3 |
Home History
| NHL | 2021/10/14 23:00 | ARZ Coyotes v CLB Blue Jackets | L | 2-8 |
| NHL Pre-Season | 2021/10/08 02:00 | ARZ Coyotes v VGS Golden Knights | W | 3-1 |
| NHL Pre-Season | 2021/10/06 02:30 | ARZ Coyotes v LA Kings | W | 4-1 |
| NHL Pre-Season | 2021/10/04 01:00 | ARZ Coyotes v DAL Stars | L | 3-6 |
| NHL Pre-Season | 2021/10/02 22:00 | ANA Ducks v ARZ Coyotes | W | 3-4 |
| NHL Pre-Season | 2021/09/30 02:00 | ARZ Coyotes v ANA Ducks | W | 4-1 |
| NHL Pre-Season | 2021/09/28 02:00 | LA Kings v ARZ Coyotes | W | 1-2 |
| NHL | 2021/05/09 02:30 | ARZ Coyotes v SJ Sharks | W | 5-4 |
Away History
| NHL | 2021/10/14 23:00 | MON Canadiens v BUF Sabres | W | 1-5 |
| NHL Pre-Season | 2021/10/09 19:00 | DET Red Wings v BUF Sabres | W | 1-3 |
| NHL Pre-Season | 2021/10/05 23:00 | BUF Sabres v PIT Penguins | L | 4-5 |
| NHL Pre-Season | 2021/10/04 23:00 | CLB Blue Jackets v BUF Sabres | L | 5-3 |
| NHL Pre-Season | 2021/10/01 23:00 | PIT Penguins v BUF Sabres | L | 2-1 |
| NHL Pre-Season | 2021/09/30 23:30 | BUF Sabres v DET Red Wings | L | 2-6 |
| NHL Pre-Season | 2021/09/28 23:00 | BUF Sabres v CLB Blue Jackets | W | 5-4 |
| NHL | 2021/05/08 19:00 | BUF Sabres v PIT Penguins | L | 0-1 |