[4] TOR Maple Leafs 1-7 PIT Penguins [6] 2021-10-23 23:00
Stadium: PPG Paints Arena
Home Manager: Mike Sullivan Away Manager: Sheldon Keefe
Head to Head
| NHL | 2020/02/21 00:00 | PIT Penguins v TOR Maple Leafs | W | 0-4 |
| NHL | 2020/02/19 00:00 | TOR Maple Leafs v PIT Penguins | L | 2-5 |
| NHL | 2019/11/17 00:00 | TOR Maple Leafs v PIT Penguins | L | 1-6 |
| NHL | 2019/02/03 00:00 | PIT Penguins v TOR Maple Leafs | W | 2-3 |
| NHL | 2018/11/03 23:00 | TOR Maple Leafs v PIT Penguins | W | 5-0 |
| NHL | 2018/10/18 23:00 | PIT Penguins v TOR Maple Leafs | L | 3-0 |
| NHL | 2018/03/11 00:00 | PIT Penguins v TOR Maple Leafs | W | 2-5 |
| NHL | 2018/02/18 00:00 | TOR Maple Leafs v PIT Penguins | L | 3-5 |
Home History
| NHL | 2021/10/22 22:00 | SJ Sharks v TOR Maple Leafs | L | 5-3 |
| NHL | 2021/10/18 23:00 | NY Rangers v TOR Maple Leafs | L | 2-1 |
| NHL | 2021/10/16 23:00 | OTT Senators v TOR Maple Leafs | W | 1-3 |
| NHL | 2021/10/14 23:00 | TOR Maple Leafs v OTT Senators | L | 2-3 |
| NHL | 2021/10/13 23:00 | MON Canadiens v TOR Maple Leafs | W | 1-2 |
| NHL Pre-Season | 2021/10/09 23:00 | OTT Senators v TOR Maple Leafs | W | 1-4 |
| NHL Pre-Season | 2021/10/05 23:00 | MON Canadiens v TOR Maple Leafs | W | 2-6 |
| NHL Pre-Season | 2021/10/04 23:00 | TOR Maple Leafs v OTT Senators | W | 3-1 |
Away History
| NHL | 2021/10/19 23:00 | DAL Stars v PIT Penguins | L | 2-1 |
| NHL | 2021/10/16 23:00 | CHI Blackhawks v PIT Penguins | W | 2-5 |
| NHL | 2021/10/14 23:00 | PIT Penguins v FLA Panthers | L | 4-5 |
| NHL | 2021/10/12 23:30 | PIT Penguins v TB Lightning | W | 6-2 |
| NHL Pre-Season | 2021/10/09 23:00 | PIT Penguins v CLB Blue Jackets | W | 4-3 |
| NHL Pre-Season | 2021/10/07 23:30 | PIT Penguins v DET Red Wings | L | 2-4 |
| NHL Pre-Season | 2021/10/05 23:00 | BUF Sabres v PIT Penguins | W | 4-5 |
| NHL Pre-Season | 2021/10/03 16:00 | DET Red Wings v PIT Penguins | W | 1-5 |