[3] DET Red Wings 6-3 CHI Blackhawks [7] 2021-10-24 23:00
Stadium: United Center
Home Manager: Jeremy Colliton Away Manager: Jeff Blashill
Head to Head
| NHL Pre-Season | 2021/10/04 23:30 | CHI Blackhawks v DET Red Wings | L | 6-4 |
| NHL Pre-Season | 2021/09/30 00:30 | DET Red Wings v CHI Blackhawks | W | 4-3 |
| NHL | 2021/04/17 23:00 | CHI Blackhawks v DET Red Wings | L | 4-0 |
| NHL | 2021/04/15 23:30 | CHI Blackhawks v DET Red Wings | W | 1-4 |
| NHL | 2021/03/01 00:00 | DET Red Wings v CHI Blackhawks | L | 2-7 |
| NHL | 2021/02/28 01:00 | DET Red Wings v CHI Blackhawks | W | 5-3 |
| NHL | 2021/02/18 00:30 | CHI Blackhawks v DET Red Wings | L | 2-0 |
| NHL | 2021/02/16 00:30 | CHI Blackhawks v DET Red Wings | L | 3-2 |
Home History
| NHL | 2021/10/23 23:00 | DET Red Wings v MON Canadiens | L | 1-6 |
| NHL | 2021/10/21 23:30 | CAL Flames v DET Red Wings | L | 3-0 |
| NHL | 2021/10/19 23:30 | CLB Blue Jackets v DET Red Wings | W | 1-4 |
| NHL | 2021/10/16 23:00 | VAN Canucks v DET Red Wings | W | 1-3 |
| NHL | 2021/10/14 23:30 | TB Lightning v DET Red Wings | L | 7-6 |
| NHL Pre-Season | 2021/10/09 19:00 | DET Red Wings v BUF Sabres | L | 1-3 |
| NHL Pre-Season | 2021/10/07 23:30 | PIT Penguins v DET Red Wings | W | 2-4 |
| NHL Pre-Season | 2021/10/06 23:00 | DET Red Wings v CLB Blue Jackets | L | 2-4 |
Away History
| NHL | 2021/10/22 00:30 | VAN Canucks v CHI Blackhawks | L | 4-1 |
| NHL | 2021/10/20 00:00 | NY Islanders v CHI Blackhawks | L | 4-1 |
| NHL | 2021/10/16 23:00 | CHI Blackhawks v PIT Penguins | L | 2-5 |
| NHL | 2021/10/15 23:00 | CHI Blackhawks v NJ Devils | L | 3-4 |
| NHL | 2021/10/14 02:00 | CHI Blackhawks v COL Avalanche | L | 2-4 |
| NHL Pre-Season | 2021/10/10 00:30 | MIN Wild v CHI Blackhawks | W | 1-5 |
| NHL Pre-Season | 2021/10/08 00:00 | CHI Blackhawks v MIN Wild | L | 2-3 |
| NHL Pre-Season | 2021/10/04 23:30 | CHI Blackhawks v DET Red Wings | W | 6-4 |