[1] FLA Panthers 3-2 DET Red Wings [3] 2021-10-29 23:00
Stadium: Little Caesars Arena
Home Manager: Jeff Blashill Away Manager: Andrew Brunette
Head to Head
| NHL | 2021/04/01 23:00 | DET Red Wings v FLA Panthers | W | 2-3 |
| NHL | 2021/03/30 23:00 | DET Red Wings v FLA Panthers | W | 1-4 |
| NHL | 2021/02/20 22:00 | FLA Panthers v DET Red Wings | L | 1-2 |
| NHL | 2021/02/20 00:00 | FLA Panthers v DET Red Wings | W | 7-2 |
| NHL | 2021/02/10 00:00 | DET Red Wings v FLA Panthers | W | 1-2 |
| NHL | 2021/02/07 20:00 | DET Red Wings v FLA Panthers | L | 4-1 |
| NHL | 2021/01/31 22:00 | FLA Panthers v DET Red Wings | W | 3-2 |
| NHL | 2021/01/31 00:00 | FLA Panthers v DET Red Wings | W | 3-2 |
Home History
| NHL | 2021/10/27 23:00 | BOS Bruins v FLA Panthers | W | 1-4 |
| NHL | 2021/10/25 23:00 | ARZ Coyotes v FLA Panthers | W | 3-5 |
| NHL | 2021/10/23 23:00 | FLA Panthers v PHI Flyers | W | 4-2 |
| NHL | 2021/10/21 23:00 | COL Avalanche v FLA Panthers | W | 1-4 |
| NHL | 2021/10/19 23:00 | FLA Panthers v TB Lightning | W | 4-1 |
| NHL | 2021/10/16 22:00 | NY Islanders v FLA Panthers | W | 1-5 |
| NHL | 2021/10/14 23:00 | PIT Penguins v FLA Panthers | W | 4-5 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
Away History
| NHL | 2021/10/27 23:00 | DET Red Wings v WAS Capitals | W | 3-2 |
| NHL | 2021/10/24 23:00 | DET Red Wings v CHI Blackhawks | W | 6-3 |
| NHL | 2021/10/23 23:00 | DET Red Wings v MON Canadiens | L | 1-6 |
| NHL | 2021/10/21 23:30 | CAL Flames v DET Red Wings | L | 3-0 |
| NHL | 2021/10/19 23:30 | CLB Blue Jackets v DET Red Wings | W | 1-4 |
| NHL | 2021/10/16 23:00 | VAN Canucks v DET Red Wings | W | 1-3 |
| NHL | 2021/10/14 23:30 | TB Lightning v DET Red Wings | L | 7-6 |
| NHL Pre-Season | 2021/10/09 19:00 | DET Red Wings v BUF Sabres | L | 1-3 |