[3] CAL Flames 5-0 BUF Sabres [6] 2021-11-19 00:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Darryl Sutter
Head to Head
| NHL | 2019/12/06 02:00 | BUF Sabres v CAL Flames | W | 3-4 |
| NHL | 2019/11/28 00:00 | CAL Flames v BUF Sabres | W | 3-2 |
| NHL | 2019/01/17 02:30 | BUF Sabres v CAL Flames | L | 4-3 |
| NHL | 2018/10/30 23:00 | CAL Flames v BUF Sabres | W | 2-1 |
| NHL | 2018/03/08 00:30 | CAL Flames v BUF Sabres | W | 5-1 |
| NHL | 2018/01/23 02:00 | BUF Sabres v CAL Flames | L | 2-1 |
| NHL | 2016/11/22 00:00 | CAL Flames v BUF Sabres | L | 2-4 |
| NHL | 2016/10/19 01:00 | BUF Sabres v CAL Flames | W | 3-4 |
Home History
| NHL | 2021/11/17 00:00 | CAL Flames v PHI Flyers | L | 1-2 |
| NHL | 2021/11/14 22:00 | CAL Flames v OTT Senators | W | 4-0 |
| NHL | 2021/11/13 00:00 | CAL Flames v TOR Maple Leafs | L | 1-2 |
| NHL | 2021/11/12 00:00 | CAL Flames v MON Canadiens | L | 2-4 |
| NHL | 2021/11/10 02:00 | SJ Sharks v CAL Flames | L | 4-1 |
| NHL | 2021/11/07 02:00 | NY Rangers v CAL Flames | W | 0-6 |
| NHL | 2021/11/05 01:00 | DAL Stars v CAL Flames | L | 4-3 |
| NHL | 2021/11/03 01:00 | NAS Predators v CAL Flames | L | 3-2 |
Away History
| NHL | 2021/11/17 00:00 | BUF Sabres v PIT Penguins | W | 2-1 |
| NHL | 2021/11/14 00:00 | TOR Maple Leafs v BUF Sabres | L | 5-4 |
| NHL | 2021/11/13 00:00 | EDM Oilers v BUF Sabres | W | 2-3 |
| NHL | 2021/11/09 00:00 | BUF Sabres v WAS Capitals | L | 3-5 |
| NHL | 2021/11/06 23:00 | DET Red Wings v BUF Sabres | L | 4-3 |
| NHL | 2021/11/05 02:00 | BUF Sabres v SEA Kraken | L | 2-5 |
| NHL | 2021/11/03 02:30 | BUF Sabres v SJ Sharks | L | 3-5 |
| NHL | 2021/10/31 20:00 | BUF Sabres v LA Kings | L | 2-3 |