[6] MON Canadiens 1-4 BUF Sabres [5] 2021-11-27 00:00
Stadium: KeyBank Center
Home Manager: Don Granato Away Manager: Dominique Ducharme
Head to Head
| NHL | 2021/10/14 23:00 | MON Canadiens v BUF Sabres | L | 1-5 |
| NHL | 2020/01/31 00:00 | MON Canadiens v BUF Sabres | W | 3-1 |
| NHL | 2019/10/09 23:00 | MON Canadiens v BUF Sabres | L | 4-5 |
| NHL | 2019/03/23 23:00 | BUF Sabres v MON Canadiens | W | 4-7 |
| NHL | 2018/11/23 21:00 | MON Canadiens v BUF Sabres | L | 2-3 |
| NHL | 2018/11/09 00:30 | BUF Sabres v MON Canadiens | L | 6-5 |
| NHL | 2018/10/25 23:00 | MON Canadiens v BUF Sabres | L | 3-4 |
| NHL | 2018/03/23 23:00 | MON Canadiens v BUF Sabres | W | 3-0 |
Home History
| NHL | 2021/11/25 00:00 | MON Canadiens v WAS Capitals | L | 3-6 |
| NHL | 2021/11/21 00:00 | NAS Predators v MON Canadiens | W | 3-6 |
| NHL | 2021/11/19 00:00 | PIT Penguins v MON Canadiens | L | 6-0 |
| NHL | 2021/11/17 00:00 | MON Canadiens v NY Rangers | L | 2-3 |
| NHL | 2021/11/15 00:00 | MON Canadiens v BOS Bruins | L | 2-5 |
| NHL | 2021/11/14 00:00 | MON Canadiens v DET Red Wings | L | 2-3 |
| NHL | 2021/11/12 00:00 | CAL Flames v MON Canadiens | W | 2-4 |
| NHL | 2021/11/10 00:00 | LA Kings v MON Canadiens | L | 3-2 |
Away History
| NHL | 2021/11/25 00:00 | BOS Bruins v BUF Sabres | L | 5-1 |
| NHL | 2021/11/23 00:00 | CLB Blue Jackets v BUF Sabres | L | 7-4 |
| NHL | 2021/11/21 23:00 | BUF Sabres v NY Rangers | L | 4-5 |
| NHL | 2021/11/19 00:00 | CAL Flames v BUF Sabres | L | 5-0 |
| NHL | 2021/11/17 00:00 | BUF Sabres v PIT Penguins | W | 2-1 |
| NHL | 2021/11/14 00:00 | TOR Maple Leafs v BUF Sabres | L | 5-4 |
| NHL | 2021/11/13 00:00 | EDM Oilers v BUF Sabres | W | 2-3 |
| NHL | 2021/11/09 00:00 | BUF Sabres v WAS Capitals | L | 3-5 |