[15] NY Islanders 1-5 FLA Panthers [3] 2021-10-16 22:00
Stadium: Amerant Bank Arena
Home Manager: Joel Quenneville Away Manager: Barry Trotz
Head to Head
| NHL | 2020/08/07 16:00 | NY Islanders v FLA Panthers | W | 5-1 |
| NHL | 2020/08/05 16:00 | NY Islanders v FLA Panthers | L | 2-3 |
| NHL | 2020/08/04 16:00 | FLA Panthers v NY Islanders | W | 2-4 |
| NHL | 2020/08/01 20:00 | FLA Panthers v NY Islanders | W | 1-2 |
| NHL | 2019/12/13 00:00 | NY Islanders v FLA Panthers | W | 3-1 |
| NHL | 2019/11/09 18:00 | FLA Panthers v NY Islanders | W | 1-2 |
| NHL | 2019/10/12 23:00 | FLA Panthers v NY Islanders | W | 2-3 |
| NHL | 2019/04/04 23:00 | NY Islanders v FLA Panthers | W | 2-1 |
Home History
| NHL | 2021/10/14 23:00 | NY Islanders v CAR Hurricanes | L | 3-6 |
| NHL Pre-Season | 2021/10/09 23:00 | NY Rangers v NY Islanders | L | 5-4 |
| NHL Pre-Season | 2021/10/05 23:00 | PHI Flyers v NY Islanders | W | 0-3 |
| NHL Pre-Season | 2021/10/02 18:00 | NJ Devils v NY Islanders | L | 2-1 |
| NHL Pre-Season | 2021/09/28 23:00 | NY Islanders v PHI Flyers | W | 3-2 |
| NHL Pre-Season | 2021/09/26 23:00 | NY Islanders v NY Rangers | W | 4-0 |
| NHL | 2021/06/26 00:00 | NY Islanders v TB Lightning | L | 0-1 |
| NHL | 2021/06/24 00:00 | TB Lightning v NY Islanders | W | 2-3 |
Away History
| NHL | 2021/10/14 23:00 | PIT Penguins v FLA Panthers | W | 4-5 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | W | 3-2 |
| NHL Pre-Season | 2021/10/01 23:00 | DAL Stars v FLA Panthers | W | 3-6 |
| NHL Pre-Season | 2021/09/30 00:00 | FLA Panthers v DAL Stars | W | 4-3 |
| NHL Pre-Season | 2021/09/26 22:00 | FLA Panthers v NAS Predators | W | 3-1 |
| NHL Pre-Season | 2021/09/26 18:00 | FLA Panthers v NAS Predators | W | 5-4 |