[5] COL Avalanche 1-4 FLA Panthers [1] 2021-10-21 23:00
Stadium: Amerant Bank Arena
Home Manager: Joel Quenneville Away Manager: Jared Bednar
Head to Head
| NHL | 2019/10/31 02:00 | FLA Panthers v COL Avalanche | L | 4-3 |
| NHL | 2019/10/18 23:00 | COL Avalanche v FLA Panthers | W | 5-4 |
| NHL | 2019/02/26 02:00 | FLA Panthers v COL Avalanche | L | 4-3 |
| NHL | 2018/12/07 00:00 | COL Avalanche v FLA Panthers | W | 5-2 |
| NHL | 2017/12/15 02:00 | FLA Panthers v COL Avalanche | W | 1-2 |
| NHL | 2017/12/10 00:00 | COL Avalanche v FLA Panthers | W | 7-3 |
| NHL | 2016/12/17 02:00 | FLA Panthers v COL Avalanche | L | 3-1 |
| NHL | 2016/10/22 23:00 | COL Avalanche v FLA Panthers | L | 2-5 |
Home History
| NHL | 2021/10/19 23:00 | COL Avalanche v WAS Capitals | L | 3-6 |
| NHL | 2021/10/17 01:00 | STL Blues v COL Avalanche | L | 5-3 |
| NHL | 2021/10/14 02:00 | CHI Blackhawks v COL Avalanche | W | 2-4 |
| NHL Pre-Season | 2021/10/09 23:00 | DAL Stars v COL Avalanche | W | 2-4 |
| NHL Pre-Season | 2021/10/08 00:00 | COL Avalanche v DAL Stars | L | 1-3 |
| NHL Pre-Season | 2021/10/06 01:00 | VGS Golden Knights v COL Avalanche | L | 7-4 |
| NHL Pre-Season | 2021/10/05 00:00 | COL Avalanche v MIN Wild | L | 1-3 |
| NHL Pre-Season | 2021/10/01 01:00 | MIN Wild v COL Avalanche | W | 4-6 |
Away History
| NHL | 2021/10/19 23:00 | FLA Panthers v TB Lightning | W | 4-1 |
| NHL | 2021/10/16 22:00 | NY Islanders v FLA Panthers | W | 1-5 |
| NHL | 2021/10/14 23:00 | PIT Penguins v FLA Panthers | W | 4-5 |
| NHL Pre-Season | 2021/10/09 22:00 | TB Lightning v FLA Panthers | L | 4-2 |
| NHL Pre-Season | 2021/10/07 23:00 | FLA Panthers v TB Lightning | L | 2-6 |
| NHL Pre-Season | 2021/10/05 23:00 | FLA Panthers v TB Lightning | W | 3-2 |
| NHL Pre-Season | 2021/10/01 23:00 | DAL Stars v FLA Panthers | W | 3-6 |
| NHL Pre-Season | 2021/09/30 00:00 | FLA Panthers v DAL Stars | W | 4-3 |