Head to Head
| NHL | 2021/03/21 01:00 | STL Blues v SJ Sharks | W | 5-2 |
| NHL | 2021/03/20 01:00 | STL Blues v SJ Sharks | W | 2-1 |
| NHL | 2021/03/09 02:00 | STL Blues v SJ Sharks | L | 2-3 |
| NHL | 2021/02/28 03:30 | STL Blues v SJ Sharks | W | 7-6 |
| NHL | 2021/02/21 00:00 | SJ Sharks v STL Blues | L | 5-4 |
| NHL | 2021/02/19 01:00 | SJ Sharks v STL Blues | W | 2-3 |
| NHL | 2021/01/21 02:00 | SJ Sharks v STL Blues | L | 2-1 |
| NHL | 2021/01/19 01:00 | SJ Sharks v STL Blues | W | 4-5 |
Home History
| NHL | 2021/11/04 02:00 | STL Blues v LA Kings | L | 2-3 |
| NHL | 2021/10/31 00:00 | CHI Blackhawks v STL Blues | W | 0-1 |
| NHL | 2021/10/29 00:00 | COL Avalanche v STL Blues | L | 4-3 |
| NHL | 2021/10/26 00:00 | LA Kings v STL Blues | W | 0-3 |
| NHL | 2021/10/24 00:00 | LA Kings v STL Blues | W | 3-7 |
| NHL | 2021/10/21 02:00 | STL Blues v VGS Golden Knights | W | 3-1 |
| NHL | 2021/10/19 02:00 | STL Blues v ARZ Coyotes | W | 7-4 |
| NHL | 2021/10/17 01:00 | STL Blues v COL Avalanche | W | 5-3 |
Away History
| NHL | 2021/11/03 02:30 | BUF Sabres v SJ Sharks | W | 3-5 |
| NHL | 2021/10/30 23:00 | WIN Jets v SJ Sharks | W | 1-2 |
| NHL | 2021/10/29 02:30 | MON Canadiens v SJ Sharks | L | 4-0 |
| NHL | 2021/10/27 00:30 | SJ Sharks v NAS Predators | L | 1-3 |
| NHL | 2021/10/24 17:00 | SJ Sharks v BOS Bruins | L | 3-4 |
| NHL | 2021/10/22 22:00 | SJ Sharks v TOR Maple Leafs | W | 5-3 |
| NHL | 2021/10/21 23:00 | SJ Sharks v OTT Senators | W | 2-1 |
| NHL | 2021/10/19 23:00 | SJ Sharks v MON Canadiens | W | 5-0 |